医学创新论坛第59期

时间：2025年2月27日（周四）下午15:00

地点：首都医科大学基础科研楼北楼一层逸夫报告厅

主持人：

Yuval Rinkevich

首都医学科学创新中心

报告人：

Maximina H. Yun

Center for Regenerative Therapies Dresden (CRTD), Technische Universität Dresden

报告题目：

On the interplay between regeneration and ageing

摘要：

Renowned for their exceptional abilities to regenerate complex structures, salamanders also display additional noteworthy traits, namely extraordinary longevity, indefinite regenerative potential, apparent lack of traditional signs of age-related decay and defiance of Gompertz’s law of mortality. As such, they constitute valuable models for addressing the nature of organismal senescence and the interplay between regeneration and ageing.

Here, I will introduce the axolotl as a novel model in ageing research, discuss our lab's efforts towards understanding how salamanders regulate hallmarks of ageing through regeneration and lifespan, and elaborate on the potential of salamander models to illuminate the basis of negligible senescence.

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