Distinguished Investigator
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
National Institutes of Health (NIH), Bethesda, MD, USA
E-mail:
wei.yang@nih.gov
Education
BA, SUNY Stony Brook, New York, USA
MA, Columbia University, New York, USA
PhD, Columbia University, New York, USA
Postdoctoral training, Columbia University and Yale University, USA
Selected Honors
National Academy of Sciences (NAS) member since 2013
American Academy of Arts and Sciences (AAAS) member since 2015
Research interests
DNA replication, DNA repair, V(D)J recombination
Representative publications
Kim J, Li CL, Chen X, Cui Y, Golebiowski FM, Wang H, Hanaoka F, Sugasawa K, Yang W. Lesion recognition by XPC, TFIIH and XPA in DNA excision repair. Nature. 2023;617(7959):170-175.
Gao Y, Cui Y, Fox T, Lin S, Wang H, de Val N, Zhou ZH, Yang W. Structures and operating principles of the replisome. Science. 2019;363(6429):eaav7003.
Gao Y, Yang W. Capture of a third Mg² is essential for catalyzing DNA synthesis. Science. 2016;352(6291):1334-7.
Kim MS, Lapkouski M, Yang W, Gellert M. Crystal structure of the V(D)J recombinase RAG1-RAG2. Nature. 2015;518(7540):507-11.
Biertümpfel C, Zhao Y, Kondo Y, Ramón-Maiques S, Gregory M, Lee JY, Masutani C, Lehmann AR, Hanaoka F, Yang W. Structure and mechanism of human DNA polymerase eta. Nature. 2010;465(7301):1044-8