Professor and Dean of the School of Public Health
Capital Medical University, Beijing, China
E-mail: Ruichen@ccmu.edu.cn

 

Education
BS, Preventive Medicine, Nanjing Medical University
PhD, Hygiene Toxicology, Nanjing Medical University
Postdoctoral training, UT Southwestern Medical Center at Dallas, Dallas, USA 
Assistant Professor, Internal Medicine, UT Southwestern Medical Center at Dallas, Dallas, USA

 

Molecular epidemiology and epigenetic mechanism in colorectal cance

 

Representative publications
Shenshen Wu, Jiajia Wang Zan Fu, Giuseppe Familiari, Michela Relucenti, Michael Aschner, Xiaobo Li, Hanqing Chen, Rui Chen (2023) Matairesinol Nanoparticles Restore Chemosensitivity and Suppress Colorectal Cancer Progression in Preclinical Models: Role of Lipid Metabolism. Nano Letter, 23(5):1970-1980. doi: 10.1021/acs.nanolett.3c00035.
Shenshen Wu, Jun Yun, Weiyan Tang, Giuseppe Familiari, Michela Relucenti, Jiong Wu, Xiaobo Li, Hanqing Chen, Rui Chen (2023) Therapeutic m6A Eraser ALKBH5 mRNA-Loaded Exosome-Liposome Hybrid Nanoparticles Inhibit Progression of Colorectal Cancer in Preclinical Tumor Models. ACS Nano, 17, 11838−11854. doi: 10.1021/acsnano.3c03050.
Qingtao Meng, Jie Xu, Jiajia Wang, Xinwei Zhang, Hongbao Yang, Hao Sun, Shenshen Wu, Michael Aschner, Xiaobo Li, Luo Zhang, Jiong Wu, Hanqing Chen, Rui Chen (2023) Investigation of the enhanced antitumour potency of CD46-specific chimeric antigen receptor-T cells in human colorectal cancer liver metastases after combination with nanotherapeutics. Nano Today. 52,101985. doi: 10.1016/j.nantod.2023.101985.
Qingtao Meng, Hao Sun, Shenshen Wu, Giuseppe Familiari, Michela Relucenti, Michael Aschner, Xiaobo Li, Rui Chen (2022). Epstein-Barr Virus-Encoded MicroRNA-BART18-3p Promotes Colorectal Cancer Progression by Targeting De Novo Lipogenesis. Adv Sci (Weinh). 9(35):e2202116. doi: 10.1002/advs.202202116.
Hao Sun, Qingtao Meng, Chengyu Shi, Hongbao Yang, Xiaobo Li, Shenshen Wu, Giuseppe Familiari, Michela Relucenti, Michael Aschner, Xuehao Wang, Rui Chen (2021). 74(5):2633-2651. Hepatology. doi: 10.1002/hep.32009.