Jihao ZHENG
Date:2024-10-16
Ph.D. Candidate, Class of 2024
 
I obtained my Master's degree from South China Agricultural University, where I focused primarily on vaccine research for viral infectious diseases in animals. During my master's programme, I developed a probiotic oral vaccine for the prevention of Porcine Epidemic Diarrhea Virus (PEDV). This probiotic vaccine addressed the shortcomings of traditional vaccines in terms of immunological persistence, gut microbiota balance, and safety, demonstrating the potential of oral vaccines in practical applications. After graduation, I underwent a year of training in the JayYu Lab at the Guangzhou National Laboratory, where my research mainly concentrated on vaccine and gene therapy tool development based on viral vectors.

 

Throughout millions of years of human struggle against viruses, we have evolved complex and diverse immune mechanisms to combat viral invasion. Meanwhile, viruses continuously mutate and evolve to evade host immune responses, creating a subtle "competition" between viruses and their hosts. This intricate process involves numerous deep mechanisms and dynamic changes, reflecting the complexity of biological systems and providing us with a vast field for exploration. As Sun Tzu said in The Art of War: "Know thy enemy and know thyself, and you can fight a hundred battles without disaster." I have a profound interest in the study of viral infection and host immunity, and I hope to gain a better understanding of the processes of viral infection and host immune responses through in-depth research into these subtle biological processes, and to truly gain the wisdom of knowing both the enemy and ourselves in order to face future viral challenges.

 

I chose to pursue my Ph.D. at the CIMR because it brings together world-class scientists and their research teams, offering exceptional scientific resources, advanced research facilities, and a rich research atmosphere. I want to conduct scientific research in this free, open, inclusive, and transparent environment, which will allow me to delve deeper into the mechanisms of viral infection and immune processes, solve current research challenges, and lay a solid foundation for future endeavors.  

 

I hope that in ten years's time, I will have made significant contributions to the field of virology while remaining passionate about scientific research.