Education&Training
Graduate
Chinese Institutes for Medical Research (CIMR), Beijing(首都医学科学创新中心)is a research organization dedicated to advancing basic and translational medical research. Our goal is to tackle fundamental problems in human health with cutting-edge technology and through interdisciplinary collaborations with world-class scientists and physicians in Beijing. CIMR will provide education and training opportunities for future medical scientists. We are committed to a science-centered framework to promote innovation in research and education through a variety of novel funding mechanisms.   
Q&A
1. For admissions, which universities are collaborating with CIMR?

CIMR collaborates with Capital Medical University for the joint admission of doctoral candidates.

 

2. What are the admission methods available at CIMR?
For Master’s degree candidates, there is an Application Assessment System for regular Ph.D. students.

 

3. Application Assessment System

Admission Targets: Fresh or former Master’s degree graduates

Timeline: Generally, the admission brochure is released between October and November each year, comprehensive assessments take place from December to April of the following year. Additional admission batches may be arranged annually based on the school’s unified enrollment schedule, with relevant information expected to be released around May. Students who pass the interview must obtain their Master’s degree and diploma, and they will start their Ph.D. studies in September of the following year.

 

4. How to choose?
 

Capital Medical University (CMU)

Chinese Institutes for Medical Research, Beijing (CIMR)

Neurobiology;

Immunology;

Pharmacology;

Biochemistry and Molecular Biology;

 

5. Where does the enrolled student’s status belong to? Which school issues the diploma?

The student status belongs to Capital Medical University, and the diploma and degree are issued by Capital Medical University after graduation.

 

6. What professional background should students who want to apply have?

Students with a strong interest in the biological sciences are encouraged to apply. Applicants should have a background in biology, computer science, mathematics, physics, chemistry, medicine, materials, electronics, and other STEM areas. They should be enthusiastic about interdisciplinary academic research and be eager to participate in scientific research.

 

7. Do applicants need to contact mentors before applying?

There is no need to contact mentors in advance. Each mentor has a certain number of admission quotas each year, and if there is an interested mentor, you can apply directly. CIMR implements a rotation system, and only admitted (or prospective) students need to contact mentors for rotation.

 

8. How many years is the length of schooling at CIMR?

Refer to the admissions brochure for the specific year.

Application Assessment System for general doctoral students (starting from master’s level)

Capital Medical University: 3-5 years.

 

9. What are the advantages of admissions at CIMR?
  • The most prestigious and worldwide mentor team: CIMR's mentors are the most competent and influential young scientists recruited from abroad, including a number of non-Chinese international scientists. They have the most extensive research skills, the most committed research zeal, the widest vision, and the most promising development prospects.
  • Multidisciplinary background, fully cross-disciplinary, and open-sharing research atmosphere: We have top scientists from the United States, Europe, and around the world, students with diverse backgrounds in biology, chemistry, physics, mathematics, computer science, biotechnology, and clinical applications, as well as technical platforms, sample libraries, databases, and clinical case resource sharing systems jointly established by multiple units.
  • Innovative medical research talent training model: CIMR collaborates closely with Capital Medical University (CMU) and more than 20 affiliated CMU hospitals, providing rich clinical research resources. It conducts basic medical research and clinical translational research centered on clinical problems.
  • Sufficient research funding: Mentors do not need to spend too much time applying for projects; most of their time can be used for research and guiding graduate students.
  • Complete supporting equipment: CIMR’s technical support platform will purchase experimental equipment and devices according to the laboratory's needs, providing the most complete experimental facilities for the laboratory.
  • The best student treatment: Compared to other research institutes, the subsidies for students at CIMR are significantly advantageous. Students can focus on research without worries.

 

10. Can students apply for admission to multiple schools’ admission projects simultaneously? How to submit application materials?

Applicants should carefully read the requirements of the corresponding admission projects, and then submit application materials according to the school’s admission brochure and CIMR’s supplementary requirements.

 

11. Is accommodation and transportation reimbursement arranged for students participating in interviews?

Offline interviews: CIMR reimburses partial transportation expenses and covers all accommodation expenses for all students participating in interviews. In special cases, online interviews may be conducted.

 

12. How are doctoral students admitted to CIMR allocated mentors? Is it necessary to contact mentors in advance?

Doctoral students at CIMR must participate in three rounds of laboratory rotations, each lasting 1-3 months. Students need to contact mentors to determine rotation-related matters before confirming admission to the first year. We encourage students to interview with mentors to determine whether the laboratory can accept rotation, the rotation time, and the planned research project. After completing three rotation rounds, students are admitted through mutual selection between mentors and students.

We encourage students who have passed the second interview to start rotating in the CIMR before enrollment, which can effectively save time after enrollment. The early rotation can be in the form of an internship or graduation design. Early rotation helps students choose the laboratory they like.

 

13. What academic exchange activities does CIMR have?

CIMR’s academic activities are rich and diverse, including series of lectures such as:

  • PI Candidate Series Lectures
  • Invited Academic Lectures
  • Specific Topic Series Lectures
  • Internal Academic Exchange Series Lectures
In addition to the above lecture series, there are international academic conferences, research progress reports, and other academic exchange activities. Students at CIMR not only benefit from exchanges and cooperation between laboratories within the institute or domestic laboratories but also exercise their abilities through face-to-face exchanges with top international peers.

 

14. What courses does CIMR have?

After doctoral students enroll, they need to complete the courses required by the university’s training program and earn the required credits. CIMR also offers special courses based on specific situations.

 

15. What are the graduation requirements for students at CIMR?

The graduation requirements for students at CIMR follow the requirements of the academic unit where their student status is located, and CIMR does not impose additional requirements.

 

16. What forms of scholarships does CIMR have?

All students studying at CIMR, in addition to applying for scholarships established by the academic unit, can also apply for the “Doctoral Graduate Scholarship” established by CIMR.

 

17. Besides research, what extracurricular activities does CIMR have?

CIMR is preparing to establish a student union to enrich students' extracurricular lives, which will organize various cultural and sports activities, including outings, fun sports meetings, and teacher-student exchange meetings.

 

18. How is the treatment of students at CIMR?
  • In addition to receiving living allowances and scholarships from the corresponding university, CIMR also provides additional living allowances, increasing year by year.
  • CIMR also sets up part-time work-study positions to help students alleviate economic pressure.
  • CIMR also provides a certain amount of book purchase allowances.
  • Participation in rich academic and team-building recreational activities.
  • Many opportunities to interact with research experts in related fields internationally, including seminars, special reports, luncheons, and other forms.

 

19. What transportation options are available?
  • Shuttle bus: Shuttle buses from student dormitories to Capital Medical University.
  • Metro: West Tieying Station.

 

20. What should students do for medical treatment?

Students can seek emergency and outpatient care for illness at designated medical insurance hospitals nearby or go to hospitals affiliated with the academic unit. Medical insurance for students studying at CIMR is implemented according to the requirements of the jointly recruiting schools.

 

21. What training courses does CIMR have? Who are they for?

CIMR holds winter school in January and summer school in July each year, targeting undergraduate and master’s students from various universities.

 

22. What is the relationship between summer/winter school and admissions at CIMR?

Training courses only involve material screening and do not include interview assessments, so they are not part of the admissions process. Admissions involve material screening and interview assessments, leading to the final selection of prospective students. Students who have attended training courses can apply for admission to CIMR. Participating in CIMR training courses helps students understand the research direction and mentors of CIMR in advance.

 

23. How to apply for training courses?

In November and December each year and May and June each year, CIMR’s official website will announce training course enrollment notices. Interested students can submit relevant materials according to the requirements of the brochure. CIMR will organize an expert group to screen and select the best candidates, and the list will be announced on CIMR’s official website.

 

24. What is the content of the training courses?

Through short-term courses, visits, team-building exchanges, short-term learning in laboratories, etc., students are encouraged to understand various research directions, current status, and cutting-edge advances in neuroscience. Students also preliminarily learn and master basic neuroscience experimental skills, enhance scientific thinking and expression abilities, and lay the foundation for future scientific research.

 

25. Are there fees for students participating in training courses? Is accommodation and transportation reimbursement arranged?

Training courses do not charge any training fees to students, and for offline courses, CIMR reimburses partial transportation expenses and covers all accommodation expenses.

 

26. How can one learn more about CIMR?

Contact: Mr. Duan

Phone: 010-83950568

Email: education@cimrbj.ac.cn

Enrollment Calendar

Application for Assessment: November each year and April of the following year.
Mentors More
PhD. Students More
Mingxin ZHANG
Ph.D. Candidate, Class of 2024 I graduated with a bachelor's degree in Clinical Medicine from University of South China and later obtained a professional master's degree in Surgery from Capital Medical University, under the supervision of Professor Liwei Zhang at Beijing Tiantan Hospital. My master’s research focused on the surgical risk prediction and assessment of brainstem glioma. I chose to pursue my doctoral studies at CIMR for several key reasons. Under the guidance of my mentors, I aim to enhance my clinical skills in skull base and brainstem surgery, thereby laying a solid foundation to become a qualified neurosurgeon. Additionally, I am eager to receive systematic research training to refine my scientific thinking and cultivate the ability to independently design and execute research projects, as well as write academic papers. This comprehensive training will enable me to effectively identify and address clinical challenges through rigorous experimentation in my future studies and clinical practice. During my doctoral studies, I hope to further delve into the surgical risks and outcome assessments of brainstem and thalamic gliomas based on my master’s research, providing more reasonable treatment guidelines for patients and scientific evidence for clinicians in strategizing surgical interventions. Additionally, I plan to explore the integration of brain function imaging with brainstem surgery, utilizing advanced imaging technologies to quantify surgical risks and their impact on neurological function, while researching how to optimize surgical plans based on patients' clinical characteristics and genetic backgrounds. I am also interested in comprehensive strategies for promoting functional recovery and aim to develop personalized rehabilitation plans post-surgery to facilitate complete recovery for patients. In the future, I hope to approach from the perspective of brain function, aiming to accurately identify the risks of postoperative functional impairment based on previous surgical risk assessments, and to take preventive measures for high-risk patients. Moreover, I aspire to develop new technologies to promote functional recovery, further improving the feasibility of surgical treatments for diffuse brainstem and thalamic gliomas. Ten years from now, I envision myself actively engaged in my beloved work as a neurosurgeon at the clinical frontlines while also possessing the potential to become a clinical scientist—integrating research with clinical practice to enhance surgical techniques and advance clinical research.
Details
Chinese Institutes for Medical Research (CIMR), Beijing(首都医学科学创新中心)is a research organization dedicated to advancing basic and translational medical research. Our goal is to tackle fundamental problems in human health with cutting-edge technology and through interdisciplinary collaborations with world-class scientists and physicians in Beijing. CIMR will provide education and training opportunities for future medical scientists. We are committed to a science-centered framework to promote innovation in research and education through a variety of novel funding mechanisms.   
Q&A
1. For admissions, which universities are collaborating with CIMR?

CIMR collaborates with Capital Medical University for the joint admission of doctoral candidates.

 

2. What are the admission methods available at CIMR?
For Master’s degree candidates, there is an Application Assessment System for regular Ph.D. students.

 

3. Application Assessment System

Admission Targets: Fresh or former Master’s degree graduates

Timeline: Generally, the admission brochure is released between October and November each year, comprehensive assessments take place from December to April of the following year. Additional admission batches may be arranged annually based on the school’s unified enrollment schedule, with relevant information expected to be released around May. Students who pass the interview must obtain their Master’s degree and diploma, and they will start their Ph.D. studies in September of the following year.

 

4. How to choose?
 

Capital Medical University (CMU)

Chinese Institutes for Medical Research, Beijing (CIMR)

Neurobiology;

Immunology;

Pharmacology;

Biochemistry and Molecular Biology;

 

5. Where does the enrolled student’s status belong to? Which school issues the diploma?

The student status belongs to Capital Medical University, and the diploma and degree are issued by Capital Medical University after graduation.

 

6. What professional background should students who want to apply have?

Students with a strong interest in the biological sciences are encouraged to apply. Applicants should have a background in biology, computer science, mathematics, physics, chemistry, medicine, materials, electronics, and other STEM areas. They should be enthusiastic about interdisciplinary academic research and be eager to participate in scientific research.

 

7. Do applicants need to contact mentors before applying?

There is no need to contact mentors in advance. Each mentor has a certain number of admission quotas each year, and if there is an interested mentor, you can apply directly. CIMR implements a rotation system, and only admitted (or prospective) students need to contact mentors for rotation.

 

8. How many years is the length of schooling at CIMR?

Refer to the admissions brochure for the specific year.

Application Assessment System for general doctoral students (starting from master’s level)

Capital Medical University: 3-5 years.

 

9. What are the advantages of admissions at CIMR?
  • The most prestigious and worldwide mentor team: CIMR's mentors are the most competent and influential young scientists recruited from abroad, including a number of non-Chinese international scientists. They have the most extensive research skills, the most committed research zeal, the widest vision, and the most promising development prospects.
  • Multidisciplinary background, fully cross-disciplinary, and open-sharing research atmosphere: We have top scientists from the United States, Europe, and around the world, students with diverse backgrounds in biology, chemistry, physics, mathematics, computer science, biotechnology, and clinical applications, as well as technical platforms, sample libraries, databases, and clinical case resource sharing systems jointly established by multiple units.
  • Innovative medical research talent training model: CIMR collaborates closely with Capital Medical University (CMU) and more than 20 affiliated CMU hospitals, providing rich clinical research resources. It conducts basic medical research and clinical translational research centered on clinical problems.
  • Sufficient research funding: Mentors do not need to spend too much time applying for projects; most of their time can be used for research and guiding graduate students.
  • Complete supporting equipment: CIMR’s technical support platform will purchase experimental equipment and devices according to the laboratory's needs, providing the most complete experimental facilities for the laboratory.
  • The best student treatment: Compared to other research institutes, the subsidies for students at CIMR are significantly advantageous. Students can focus on research without worries.

 

10. Can students apply for admission to multiple schools’ admission projects simultaneously? How to submit application materials?

Applicants should carefully read the requirements of the corresponding admission projects, and then submit application materials according to the school’s admission brochure and CIMR’s supplementary requirements.

 

11. Is accommodation and transportation reimbursement arranged for students participating in interviews?

Offline interviews: CIMR reimburses partial transportation expenses and covers all accommodation expenses for all students participating in interviews. In special cases, online interviews may be conducted.

 

12. How are doctoral students admitted to CIMR allocated mentors? Is it necessary to contact mentors in advance?

Doctoral students at CIMR must participate in three rounds of laboratory rotations, each lasting 1-3 months. Students need to contact mentors to determine rotation-related matters before confirming admission to the first year. We encourage students to interview with mentors to determine whether the laboratory can accept rotation, the rotation time, and the planned research project. After completing three rotation rounds, students are admitted through mutual selection between mentors and students.

We encourage students who have passed the second interview to start rotating in the CIMR before enrollment, which can effectively save time after enrollment. The early rotation can be in the form of an internship or graduation design. Early rotation helps students choose the laboratory they like.

 

13. What academic exchange activities does CIMR have?

CIMR’s academic activities are rich and diverse, including series of lectures such as:

  • PI Candidate Series Lectures
  • Invited Academic Lectures
  • Specific Topic Series Lectures
  • Internal Academic Exchange Series Lectures
In addition to the above lecture series, there are international academic conferences, research progress reports, and other academic exchange activities. Students at CIMR not only benefit from exchanges and cooperation between laboratories within the institute or domestic laboratories but also exercise their abilities through face-to-face exchanges with top international peers.

 

14. What courses does CIMR have?

After doctoral students enroll, they need to complete the courses required by the university’s training program and earn the required credits. CIMR also offers special courses based on specific situations.

 

15. What are the graduation requirements for students at CIMR?

The graduation requirements for students at CIMR follow the requirements of the academic unit where their student status is located, and CIMR does not impose additional requirements.

 

16. What forms of scholarships does CIMR have?

All students studying at CIMR, in addition to applying for scholarships established by the academic unit, can also apply for the “Doctoral Graduate Scholarship” established by CIMR.

 

17. Besides research, what extracurricular activities does CIMR have?

CIMR is preparing to establish a student union to enrich students' extracurricular lives, which will organize various cultural and sports activities, including outings, fun sports meetings, and teacher-student exchange meetings.

 

18. How is the treatment of students at CIMR?
  • In addition to receiving living allowances and scholarships from the corresponding university, CIMR also provides additional living allowances, increasing year by year.
  • CIMR also sets up part-time work-study positions to help students alleviate economic pressure.
  • CIMR also provides a certain amount of book purchase allowances.
  • Participation in rich academic and team-building recreational activities.
  • Many opportunities to interact with research experts in related fields internationally, including seminars, special reports, luncheons, and other forms.

 

19. What transportation options are available?
  • Shuttle bus: Shuttle buses from student dormitories to Capital Medical University.
  • Metro: West Tieying Station.

 

20. What should students do for medical treatment?

Students can seek emergency and outpatient care for illness at designated medical insurance hospitals nearby or go to hospitals affiliated with the academic unit. Medical insurance for students studying at CIMR is implemented according to the requirements of the jointly recruiting schools.

 

21. What training courses does CIMR have? Who are they for?

CIMR holds winter school in January and summer school in July each year, targeting undergraduate and master’s students from various universities.

 

22. What is the relationship between summer/winter school and admissions at CIMR?

Training courses only involve material screening and do not include interview assessments, so they are not part of the admissions process. Admissions involve material screening and interview assessments, leading to the final selection of prospective students. Students who have attended training courses can apply for admission to CIMR. Participating in CIMR training courses helps students understand the research direction and mentors of CIMR in advance.

 

23. How to apply for training courses?

In November and December each year and May and June each year, CIMR’s official website will announce training course enrollment notices. Interested students can submit relevant materials according to the requirements of the brochure. CIMR will organize an expert group to screen and select the best candidates, and the list will be announced on CIMR’s official website.

 

24. What is the content of the training courses?

Through short-term courses, visits, team-building exchanges, short-term learning in laboratories, etc., students are encouraged to understand various research directions, current status, and cutting-edge advances in neuroscience. Students also preliminarily learn and master basic neuroscience experimental skills, enhance scientific thinking and expression abilities, and lay the foundation for future scientific research.

 

25. Are there fees for students participating in training courses? Is accommodation and transportation reimbursement arranged?

Training courses do not charge any training fees to students, and for offline courses, CIMR reimburses partial transportation expenses and covers all accommodation expenses.

 

26. How can one learn more about CIMR?

Contact: Mr. Duan

Phone: 010-83950568

Email: education@cimrbj.ac.cn

Enrollment Calendar

Application for Assessment: November each year and April of the following year.
Mentors
Guomin LI
Distinguished Investigator
Majors for Enrollment: Biochemistry and Molecular Biology NeurobiologyOncology Immunology Cell Biology Dr. Guomin Li received his bachelor’s and PhD degrees from Wuhan University’s Department of Biology and Wayne State University’s Department of Chemistry, respectively. He worked as a postdoctoral Investigator in the laboratory of Dr. Paul Modrich, the 2015 Nobel Laureate in Chemistry, at Duke University, where he made substantial contributions to the award-winning work. Professor Li was an Endowed Professor at the University of Texas Southwestern Medical Center and the director of the Reece A. Overcash, Jr. Center for Research on Colon Cancer before he was appointed a Distinguished Investigator at the Capital Medical Science Innovation Center. Professor Li’s laboratory is dedicated to studying DNA mismatch repair (MMR), a critical cellular mechanism ensuring the accuracy of DNA replication. His work contributes to understanding MMR and its role in cancer susceptibility and treatment. He discovered that MMR defects form the molecular basis for various hereditary and sporadic cancers. Professor Li purified and identified most components required for human MMR and reconstructed human MMR reactions in vitro. His lab found that epigenetic factors, including histone modifications and mutations, are crucial components and regulators of MMR. Recently, his laboratory elucidated how MMR-deficient tumors activate the cGAS-STING pathway to promote tumor immune checkpoint therapy.
Deguang LIANG
Assistant Investigator
Majors for Enrollment: Biochemistry and Molecular Biology  Dr. Deguang Liang received his bachelor’s degree in Pharmaceutical Sciences from Sun Yat-sen University, and his Ph.D. in Microbiology from Institut Pasteur of Shanghai, Chinese Academy of Sciences. He conducted his postdoctoral research with Dr. Xuejun Jiang at Memorial Sloan Kettering Cancer Center. He will join CIMR as assistant investigator in 2024. His previous studies have been published in prestigious journals such as Cell, Molecular Cell, and Cell Research, among others. Dr. Liang’s lab is dedicated to studying the molecular regulation and biological function of phospholipid (PL) metabolism pathways (e.g., PL de novo synthesis, remodeling, transport, etc.) under different physiological and pathological conditions. PLs are major components of cell membranes, and the dynamic changes in PL composition, on the one hand, regulate the physicochemical properties of cell membranes and influence cellular functions (such as cell migration, phagocytosis, exocytosis, autophagy, mitochondrial aerobic respiration, etc.). On the other hand, they also modulate the sensitivity of cells to ferroptosis (an emerging form of regulated cell death caused by iron-mediated PL peroxidation) and affect the occurrence and progression of related diseases (such as tumors, neurodegenerative diseases, ischemia-reperfusion injury, etc.). Therefore, investigating the intricate feedback regulation of cellular PL metabolism pathways holds significant importance for both basic and translational research.
Lin MEI
Distinguished Investigator
Majors for Enrollment: Immunology Neurology Neurobiology Psychiatry and Mental Health Biochemistry and Molecular Biology Dr. Lin Mei pioneered our apprehension of the development and function of synapses - nerve cell contacts critical to the communication between neurons. He revealed molecular mechanisms of the formation of the neuromuscular junction (NMJ), a special synapse critical to our mobility. He discovered that LRP4, a molecule critical to NMJ formation, serves as the receptor for agrin, solving a decade-old mystery. By solving the crystal structure of an agrin-LRP4 complex, he revealed how signal is transduced from agrin to the downstream kinase MuSK. Dr. Mei also uncovered LRP4 antibodies as a new biomarker for myasthenia gravis that otherwise cannot be diagnosed. He recently revealed rapsyn, a classic “adapter protein”, undergoes phase condensation and is in fact an enzyme whose activity is necessary for NMJ formation, uncovering brand-new mechanisms. Dr. Mei has also discovered an important homeostatic control of brain activity by neuregulin 1 and its receptor ErbB4, both risk genes of major depression and schizophrenia. Dr. Mei’s paradigm-shifting works have been described in neuroscience textbooks and have an enormous impact on clinical practice. For example, a test he invented to detect LRP4 antibodies has been used worldwide in the clinic to diagnose myasthenia gravis. Dr. Mei led a consortium of seventeen clinical centers in the US to study newly identified biomarkers in myasthenia gravis. Many of his trainees including 12 PhD students have become independent scientists.       Dr. Mei is currently the founding Director, Chinese Institutes for Medical Research, Beijing. In 2017-2023, he was the Chair, Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio and the founding Director of Cleveland Brain Health Initiative that brings together the collaborative expertise of ~500 scientists and clinicians in Cleveland to improve brain health. Earlier, he was on faculty at the University of Virginia, University of Alabama at Birmingham, and Medical College of Georgia where he established a new Department of Neuroscience and Regenerative Medicine.   
Shao-Cong SUN
Distinguished Investigator
Majors for Enrollment: Immunology Oncology Cell BiologyBiochemistry and Molecular Biology  B.S. in Department of Biology, Hebei University, ChinaM.S. in Department of Microbiology, Stockholm University, SwedenPh.D. in Department of Microbiology, Stockholm University, Sweden 2024-PresentDistinguished Investigator, Director of Institute for Immunology,Chinese Institutes for Medical Research, Beijing, China2024-PresentChair Professor, Capital Medical University, China2017-2022Deputy Chair, Department of Immunology, The University of TexasMD Anderson Cancer Center, USA2014-2022Director, Center for Inflammation and Cancer, The University ofTexas MD Anderson Cancer Center, USA2012-2022Associate Director, Center for Cancer Immunology Research, TheUniversity of Texas MD Anderson Cancer Center, USA2013-2022Moshe Talpaz Endowed Chair in Immunology, The University of TexasMD Anderson Cancer Center, USA2011-2013M.R.Evely Hudson Foundation Endowed Professor, The University ofTexas MD Anderson Cancer Center, USA2007-2022Professor, Department of Immunology, The University of Texas MDAnderson Cancer Center, USA2006-2007Distinguished professor, Department of Microbiology & Immunology,Pennsylvania State University College of Medicine, USA2002-2006Professor, Department of Microbiology & Immunology,Pennsylvania State University College of Medicine, USA1999-2002Associate Professor, Department of Microbiology & Immunology,Pennsylvania State University College of Medicine, USA1994-1999Assistant Professor, Department of Microbiology & Immunology,Pennsylvania State University College of Medicine, USA1992-1994Postdoctoral Fellow, The Gladstone Institute of Virology and ImmunologyUniversity of California, San Francisco (advisor: Warner Greene) The main research in Sun lab is to investigate the molecular mechanisms of anticancer immunity, autoimmunity and inflammatory diseases, focusing on the function and regulation of T cells.
Liming WANG
Investigator
Majors for Enrollment: Neurobiology Biochemistry and Molecular Biology B.S. in School of Life Sciences, Peking University, ChinaPh.D. in Division of Biology, California Institute of Technology, USA 2024-PresentInvestigator, Director of Institute for Genetics and Molecular Medicine, Chinese Institutes for Medical Research, Beijing, China2024-PresentProfessor, Capital Medical University, China2022-2024Senior Investigator and Deputy Director, Institute of Molecular Physiology, Shenzhen Bay Laboratory, China2014-2022Professor and Senior Investigator, Life Sciences Institute, Zhejiang University, China2013-2014Consultant, Boston Consulting Group, USA2011-2013Bowes Research Fellow, Department of Molecular Cell Biology, University of California, Berkeley, USA In the past decade, the research work of Wang laboratory has mainly focused on the neural regulatory mechanisms of organismal energy and nutrient homeostasis. More specifically, the Wang lab has been interested in understanding the follow questions: how the brain detects changes in the internal storage of energy and vital nutrients; how the brain initiates various behaviors to fulfill the requirement of energy and vital nutrients in shortage; how sustained lifestyle challenges affects the function of the brain to maintain energy and nutrient homeostasis; how the brain coordinates food intake with other important innate behaviors such as social, sex, and sleep; how the brain interacts with peripheral organs to coordinate metabolic remodeling upon metabolic changes.
Yuval RINKEVICH
Distinguished Investigator
Majors for Enrollment: Physiology Cell Biology Biochemistry and Molecular Biology Bachelor of Science (BSc), Faculty of Life Sciences, Tel-Aviv University, IsraelMaster of Science (MSc), Israel Institute of Technology, Haifa, IsraelDoctorate in Biology (PhD), Israel Institute of Technology, Haifa, Israel  2024-PresentDistinguished Investigator and Director, Institute for Regenerative Biology and Medicine, Chinese Institutes for Medical Research, Beijing, China2024-PresentChair Professor, Capital Medical University, China2021-2024Institute Director, Institute for Regenerative Biology and Medicine (IRBM), Helmholtz Center Munich, GermanySince 2019Tenured Principal Investigator, Institute for Lung Biology and Disease; Helmholtz Center Munich, Germany2015-2019PI of Research Group, Institute for Lung Biology and Disease; Helmholtz Center Munich, Germany2014-2015Basic Life Science Research Associate, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University (Prof. Irving L. Weissman, Advisor)2008-2014Post doctorate, Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University (Prof. Irving L. Weissman, Advisor) The lab of Dr. Rinkevich explores the stem cells, embryonic lineages and molecular basis of tissue repair and regeneration as foundation for therapeutic use. Research direction includes discovery of fibroblast lineages in the transition from scarless healing to scar forming tissue responses. His latest work describing the fascia connective tissue, and its mobilization in injury repair in multiple organ systems is reinventing the way we look at tissue repair and regeneration, opening a new biological context to treat and resolve fibrotic diseases.  
Honghu ZHU
Associate Investigator
Majors for Enrollment: Internal Medicine Oncology Biochemistry and Molecular Biology  Professor Hong-Hu Zhu got his Ph.D. from Peking University under the supervision of Professor Daopei Lu, an academician of the Chinese Academy of Engineering. He is a member of the International Acute Promyelocytic Leukemia (APL) Foundation, a member of the Asia‐Pacific Leukemia Consortium, a standing committee member of the Hematology-Oncology Committee of the Chinese Anti-Cancer Association, an executive committee member of the China Association of Chinese Medicine Blood Disease Branch, a committee member of the Leukemia and Lymphoma Group of Chinese Society of Hematology in Chinese Medical Association, and the deputy director of the Cell Analysis Committee, Chinese Society of Biotechnology. Professor Zhu has worked in hematology for 29 years, specializing in clinical and translational research in acute leukemia. His primary academic achievements include: First, establishing a unique chemo-free outpatient treatment model with oral arsenics ad ATRA for acute promyelocytic leukemia (APL), with a cure rate of more than 95%.【J Clin Oncol(2013)、N Eng J Med(2014a,2014b)、Lancet Oncol(2018)、Blood(2016, 2018, 2019),J Hematol Oncol(2022)】 Second, establishing the DAV (daunorubicin, cytarabine, and homoharringtonine) regimen as front-line treatment for newly diagnosed acute myeloid leukemia (AML), with a complete remission  rate exceeding 90%.【Lancet Haematol 2022】 Third, Pioneering the definition of a new subtype of leukemia, RARG rearranged AML for the first time internationally.【Leukemia 2018、Leuk Res 2019, Blood Advance 2023】 Professor Zhu is at the forefront of developing efficient, low-toxicity leukemia treatment procedures and tailored diagnostic and therapeutic approaches in China. 
PhD. Students
Mingxin ZHANG
Ph.D. Candidate, Class of 2024 I graduated with a bachelor's degree in Clinical Medicine from University of South China and later obtained a professional master's degree in Surgery from Capital Medical University, under the supervision of Professor Liwei Zhang at Beijing Tiantan Hospital. My master’s research focused on the surgical risk prediction and assessment of brainstem glioma. I chose to pursue my doctoral studies at CIMR for several key reasons. Under the guidance of my mentors, I aim to enhance my clinical skills in skull base and brainstem surgery, thereby laying a solid foundation to become a qualified neurosurgeon. Additionally, I am eager to receive systematic research training to refine my scientific thinking and cultivate the ability to independently design and execute research projects, as well as write academic papers. This comprehensive training will enable me to effectively identify and address clinical challenges through rigorous experimentation in my future studies and clinical practice. During my doctoral studies, I hope to further delve into the surgical risks and outcome assessments of brainstem and thalamic gliomas based on my master’s research, providing more reasonable treatment guidelines for patients and scientific evidence for clinicians in strategizing surgical interventions. Additionally, I plan to explore the integration of brain function imaging with brainstem surgery, utilizing advanced imaging technologies to quantify surgical risks and their impact on neurological function, while researching how to optimize surgical plans based on patients' clinical characteristics and genetic backgrounds. I am also interested in comprehensive strategies for promoting functional recovery and aim to develop personalized rehabilitation plans post-surgery to facilitate complete recovery for patients. In the future, I hope to approach from the perspective of brain function, aiming to accurately identify the risks of postoperative functional impairment based on previous surgical risk assessments, and to take preventive measures for high-risk patients. Moreover, I aspire to develop new technologies to promote functional recovery, further improving the feasibility of surgical treatments for diffuse brainstem and thalamic gliomas. Ten years from now, I envision myself actively engaged in my beloved work as a neurosurgeon at the clinical frontlines while also possessing the potential to become a clinical scientist—integrating research with clinical practice to enhance surgical techniques and advance clinical research.
Xiang LI
Ph.D. Candidate, Class of 2024 I graduated with a Bachelor's degree from Shandong First Medical University and a Master's degree from Beijing University of Technology. During my master's program, my primary research focus was exploring the connection between redox homeostasis and ferroptosis in breast cancer cells. Since the establishment of CIMR last year, I have been closely following its progress. In January 2024, I enrolled in CIMR's Winter School program. Over the course of seven days, I attended lectures by esteemed medical scientists and physician-scientists who shared their research achievements and life experiences, gaining a deep understanding of CIMR's educational philosophy and graduate training system. In September, I officially became a member of CIMR and embarked on the laboratory rotation phase. After two months of rotation, I have found CIMR to be a dynamic and innovative research institute, boasting a domestically top-tier team of Principal Investigators (PIs), ample research funding, advanced platform facilities, and abundant academic resources. The research directions of the PIs all originate from clinical practical problems, aiming at the clinical translation of research achievements and ultimately alleviating and eliminating patient suffering. As a graduate student, under the guidance of the PIs, I have access to the forefront of research topics, can expand my research direction based on my interests, and receive professional scientific training. Currently, my research interest primarily lies in exploring the molecular mechanisms underlying the regulation of ferroptosis by phospholipid metabolism in tumor cells, with the hope of developing novel therapeutic strategies targeting phospholipid metabolism and ferroptosis for tumor treatment in the future.
Qian GUO
Ph.D. Candidate, Class of 2024 I graduated with a master's degree from the Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, specializing in cell biology. After graduation, I joined CIMR to pursue my Ph.D.  I first learned about CIMR through a post on Professor Yi Rao's WeChat public account. I was attracted by the excellent faculty and the philosophy of ‘scientists managing scientists’, which motivated me to apply. Having been here for a few months now, I am deeply impressed by the vibrant research atmosphere and feel honored to be part of this family. My research interest lies in immunology—a field intimately connected to human health. Recent breakthroughs in B-cell and T-cell development and therapy, particularly in TCR and BCR engineering and related signaling pathways, have been remarkable.  Over the next decade, I aspire to dedicate myself to this field, deepening my understanding through learning and discussions with mentors, senior students, and peers. I hope to make a small but meaningful contribution to the treatment of related diseases. Perception of scientific research: I think scientific research is a process of cultivation, which requires cooperation and of course patience, perseverance, optimism and interest, in which we will deepen our understanding and exercise to make ourselves better. A personal motto guides me, and I’d like to share it for inspiration: "Be a person of length, healthy in body and mind, which is the foundation of learning and work;Be a person with width, learn life skills in addition to professional knowledge, read more, watch more, think more, walk more, listen more, and keep enriching your life;Be a person with depth, look beyond surfaces, deliberate thoroughly, and make choices without regret;Be a person with height, elevate your character, respond with composure, and face challenges magnanimously;Be a person with dimension, navigate diverse roles (parent, mentor, professional, etc.) with grace, crafting a life of both refinement and joy." May we all ride our dreams and find our spiritual haven.
Jihao ZHENG
Ph.D. Candidate, Class of 2024 I obtained my Master's degree from South China Agricultural University, where I focused primarily on vaccine research for viral infectious diseases in animals. During my master's programme, I developed a probiotic oral vaccine for the prevention of Porcine Epidemic Diarrhea Virus (PEDV). This probiotic vaccine addressed the shortcomings of traditional vaccines in terms of immunological persistence, gut microbiota balance, and safety, demonstrating the potential of oral vaccines in practical applications. After graduation, I underwent a year of training in the JayYu Lab at the Guangzhou National Laboratory, where my research mainly concentrated on vaccine and gene therapy tool development based on viral vectors. Throughout millions of years of human struggle against viruses, we have evolved complex and diverse immune mechanisms to combat viral invasion. Meanwhile, viruses continuously mutate and evolve to evade host immune responses, creating a subtle "competition" between viruses and their hosts. This intricate process involves numerous deep mechanisms and dynamic changes, reflecting the complexity of biological systems and providing us with a vast field for exploration. As Sun Tzu said in The Art of War: "Know thy enemy and know thyself, and you can fight a hundred battles without disaster." I have a profound interest in the study of viral infection and host immunity, and I hope to gain a better understanding of the processes of viral infection and host immune responses through in-depth research into these subtle biological processes, and to truly gain the wisdom of knowing both the enemy and ourselves in order to face future viral challenges. I chose to pursue my Ph.D. at the CIMR because it brings together world-class scientists and their research teams, offering exceptional scientific resources, advanced research facilities, and a rich research atmosphere. I want to conduct scientific research in this free, open, inclusive, and transparent environment, which will allow me to delve deeper into the mechanisms of viral infection and immune processes, solve current research challenges, and lay a solid foundation for future endeavors.   I hope that in ten years's time, I will have made significant contributions to the field of virology while remaining passionate about scientific research.
Shuqin JI
Ph.D. Candidate, Class of 2024 I graduated from Xinxiang Medical University with a bachelor's degree in Clinical Medicine (Physician Education and Training Programme of Excellence). Subsequently, I pursued and obtained my master's degree in Pathology at Chongqing Medical University. During my postgraduate studies, I immersed myself in scientific research at the Center for Molecular Medicine and Oncology Research, focusing on identifying novel cancer biomarkers and investigating their role in cancer pathogenesis. Additionally, I served as a research assistant at the Brain and Intelligence Research Key Laboratory of the Chongqing Education Commission, affiliated to the Third Military Medical University. The Chinese Institutes for Medical Research (CIMR), Beijing is dedicated to advancing medical science and improving human health through groundbreaking biomedical research. CIMR is committed to strengthening the innovation and translational capabilities of medical science and raising the standards of disease diagnosis and treatment. The Institute brings together a community of world-class scientists and their research teams, and collaborates closely with Beijing's premier medical education and scientific research resources. Together, we foster a multidisciplinary research environment that nurtures a new paradigm of scientific exploration, drives the integration of medicine, education, research, and industry, and cultivates top-tier talent poised to lead in the era of medical innovation. I am deeply honored to continue my scientific exploration on this prestigious platform. The advent of high-throughput sequencing, single-cell sequencing, and bioinformatics has revolutionized our understanding of the immune system's intricate network, shedding light on the interactions among immune cells and the mechanisms underlying immune regulation. These advancements hold immense potential for scientific discovery and for advancing human health and disease management. In particular, cancer therapy remains a formidable challenge, with the complexity of tumor immune microenvironments and the quest for novel immunotherapeutic targets at the forefront. I aim to leverage single-cell transcriptome sequencing to map cellular dynamics within tumor microenvironments, uncovering new subsets of macrophages and deepening our understanding of these complex systems. This work is essential for developing innovative immunotherapeutic strategies. Furthermore, I am eager to explore the immune system's pivotal role in various disease pathogeneses and treatments, and to contribute to the discovery of groundbreaking therapeutic approaches. I aspire to be a catalyst for discovery, driven by a spirit of exploration and a commitment to making a tangible impact through research. I will maintain an unwavering curiosity and inquisitiveness, coupled with a rigorous and meticulous approach to my work. A decade from now, I envision myself as a respected immunology researcher, having achieved significant milestones, tackling key scientific questions, and seeing my research findings translated into clinical practice, thereby contributing positively to the fields of life sciences and clinical medicine. I also hope to become an exemplary mentor, guiding and inspiring a new generation of scientists to pursue their academic aspirations with passion and dedication. Above all, I will continue to cherish life's passions and the joy of unraveling life's mysteries, with enduring vigor and love in my heart. From the steady dawn of each day, small yet significant strides, like the quiet accumulation of morning dew, will persist, and from this perseverance, brilliance and radiance shall emerge. 
Xinjie LI
Ph.D. Candidate, Class of 2024 I graduated from Hebei Medical University majoring in pharmacy and am now a PhD student in the CIMR. As the forward position of scientific research and innovation, CIMR brings together top scientific research talents and rich academic resources at home and abroad. It not only has advanced experimental equipment and research platform, but also holds high-level academic seminars frequently. Choosing the CIMR to study for a doctorate means standing at the forefront of scientific research. Here I can explore unknown scientific problems with experts from different fields, which can not only inspire new research inspiration, but also cultivate my ability to solve complex problems and lay a solid foundation for my future scientific research career. I am very interested in the research in the field of neuroscience, especially the transmission mechanism of neural signals, neural plasticity and their mechanism in the process of learning and memory. In addition, I have unlimited expectations for the potential application of neuroscience in the field of artificial intelligence, and dream of learning from the excellent working way of the brain to develop more advanced and efficient algorithms and computational models. Looking forward to the next decade, I look forward to growing into an influential researcher in the field of neuroscience. I am eager to leave my footprint in the academic palace, not only publishing a number of high-quality research papers with far-reaching impact in top academic journals, but also leaving my name in the frontier exploration of neuroscience. I dream of participating in or leading a series of landmark research projects that can not only deepen our understanding of neural mechanisms, but also inject new vitality into the development of artificial intelligence. promote cross-integration and common progress in the two fields.
Yunlei WEI
Ph.D. Candidate, Class of 2024 I completed both my bachelor's and master's degrees at the School of Medicine, Anhui University of Science and Technology, where my master's research focused on the prevention of postoperative esophageal stricture. Through my years of study and research, I have gained a deep understanding of the complexity and challenges in the medical field. I learned that the Chinese Institutes for Medical Research is a cutting-edge, multidisciplinary research platform with highly skilled scientists and outstanding research teams. The center also collaborates closely with top-tier medical education and research resources in the capital, which fills me with great anticipation and admiration. Such an environment not only fosters scientific innovation but also provides valuable support and resources for my academic growth.  During my PhD studies, I aim to maintain a rigorous and diligent approach to learning, steadily advancing my research, and continuously accumulating knowledge and skills to achieve both theoretical and practical breakthroughs. I am particularly interested in the mechanisms of the immune system's role in diseases such as cancer, specifically how it functions in the occurrence and treatment of these diseases. I hope to gain a deeper understanding of the immune system's responses and regulatory mechanisms in various pathological conditions through basic research. Based on this, I aspire to discover ways to harness the immune system's potential, advancing the application of immunotherapy in disease treatment, and ultimately contributing to human health. Looking ahead, I envision myself, in ten years, having made significant progress in the field of tumor immunology, establishing myself as a specialized researcher in this area. I hope to lead my own research team, continually driving breakthrough advancements and contributing to the forefront of medical research on the international stage. At the same time, I hope that my research will tangibly benefit patients, helping more people overcome disease, and realizing the goal of "academic research serving human health". 
Jiajun YANG
Ph.D. Candidate, Class of 2024 I completed both my bachelor's and master's degrees in Stomatology at Sun Yat-sen University, following a 5+3 academic system. During my master's program, I underwent Standardized Residents Training at Hospital of Stomatology, Sun Yat-sen University, where I also engaged in research focused on the physicochemical properties of dental restorative materials. After graduation, I worked as a dentist in oral diagnosis and treatment. Through this experience, I deeply felt the contradiction between patients' pursuit of health and the limitations of existing medical practices. This conflict reignited my passion for scientific research, prompting me to leave my clinical position and pursue a Ph.D. at CIMR. I hope to strengthen the connection between clinical and fundamental research to facilitate the translation of scientific discoveries into practical applications, ultimately benefiting more patients. I am particularly interested in biochemistry and molecular biology, as they form a crucial foundation of life sciences. In the future, I aim to delve into the mechanisms of interactions among different molecular pathways during tumor onset, progression, and prognosis, seeking new breakthroughs for clinical cancer treatment. Throughout my studies at CIMR, I will strive to enhance my research skills and critical thinking. Regardless of my future career path, I will remain committed to the oath I took as a medical student: to dedicate my life to the health and well-being of humanity.
Minwei LI
Ph.D. Candidate, Class of 2024 I have a bachelor's degree from Chengdu University of Traditional Chinese Medicine and a master's degree from Wenzhou Medical University. During my master's degree, my research direction was the development of new methods for detection of infectious diseases. The main work is to develop a fast, convenient and efficient monitoring method for trace pathogens of bloodstream infection by transforming bacteriophages into probes using crisper technology and combining them with microfluidic chips.CIMR as one of the three major sectors of the development of Capital Medical University, before I came in, I tried to apply just because of the recommendation of my senior sister. But in retrospect, I'm glad I made that choice once. CIMR has a strong academic atmosphere, and the communication between teachers and students is particularly open (students are encouraged to question and criticize), which is rare among the colleges and research institutions I have come into contact with. The research group rotation mechanism also gives students the opportunity to learn more about the research direction and choose the topic that suits them. At the same time, the center also has a lot of academic activities, such as the forum and lunch meeting every Wednesday (having a meal with the report teacher) and Journal Club for students every Friday, which can constantly develop and train students' scientific research literacy. I think this is very attractive for students who want to improve their academic ability. One year after the establishment of CIMR, there are many attractive new highlights (high subsidies, adequate resources, open thinking, novel administrative mechanisms, etc.), but there are also many new services and new policies to be formulated and developed. Such as dormitories, rotations, student work, etc. (I don't know if I can say) but I believe that with such open tutors and administrative teachers, it is only a matter of time before these problems are solved. The future teachers and sisters will usher in a better CIMR.As for the scientific problems to be solved in the future, in a narrow sense, it is what the direction of the supervisor wants to solve; Broadly speaking, I hope to use the ability to discover problems, design experiments and solve problems cultivated during the years of doctoral study to solve current people's health problems. I will work hard and hope that 10 years later, my conscience is clear.
Cuidie WANG
Ph.D. Candidate, Class of 2024 I graduated from Hebei Medical University with a degree in Basic Medicine. During my undergraduate studies, my research internship focused on emotional respiratory regulation, and I participated in the national key project titled "Mechanisms of Respiratory Abnormalities Induced by Anxiety-like Behavior." This project centers on the neurobiological basis of respiratory changes induced by anxiety emotions and proposes for the first time that acute restraint stress models activate neurons in the central amygdala. By combining optogenetics with behavioral experiments and non-invasive volume plethysmography in small animals, I validated the role of the central amygdala in anxiety-like behaviors from multiple perspectives and explored how it induces respiratory changes through the regulation of the pre-Bötzinger complex, providing a theoretical basis for understanding the relationship between anxiety emotions and respiratory regulation. For my graduation design project, I focused on "The Role of the Periventricular Nucleus in the Process of Extinction of Acute Stress-Related Anxiety-like Behaviors," investigating the neural circuit mechanisms of the periventricular nucleus in stress-related anxiety-like behaviors. Given that current clinical treatments for stress-related mental illnesses and their efficacy remain unsatisfactory, elucidating the brain mechanisms that trigger anxiety disorders due to stress is expected to provide potential directions for new treatment strategies. CIMR features a multidisciplinary modern medical research system dedicated to establishing a goal-oriented research model centered on medicine, promoting the translation of basic research into clinical medical results. Collaborations with various hospitals allow research to be more closely aligned with clinical needs, facilitating the rapid translation of research outcomes, while a new management and research model lays the foundation for the center's long-term development. I have a keen interest in the field of neurobiology. With the increasing social pressures, emotional problems are becoming more common, and neurobiology provides a foundation for understanding both animal and human behaviors. By studying how the nervous system affects emotions, learning, memory, and decision-making, we can delve into complex biological behaviors. Furthermore, understanding the mechanisms of neurobiology aids in the development of drugs for mental illnesses and offers theoretical support for addressing issues such as addiction, mental disorders, and social behavior abnormalities. Currently, the diagnosis of various emotional disorders primarily relies on scale assessments, with few laboratory diagnostic methods available. Therefore, I hope to analyze neural network activities related to emotional disorders to identify potential biological markers for early diagnosis, predicting disease progression, and assessing treatment effectiveness. Additionally, in-depth research on neural networks can reveal differences in emotional responses and manifestations of emotional disorders among individuals, which is crucial for personalized medicine and precision treatment. Through continuous research training, I aspire to achieve significant accomplishments in my chosen field, publish high-impact papers, and establish a reputation in academia and industry. I aim to combine interdisciplinary knowledge and methods to tackle complex scientific problems and drive research innovation. Most importantly, I will maintain a curiosity for new knowledge and technologies, embrace challenges, and continuously learn and improve to adapt to the rapidly evolving scientific landscape. 
Yida CAO
Ph.D. Candidate, Class of 2024 I began my academic journey in Capital Medical University and went on to pursue a master's degree in Beijing Anzhen Hospital affiliated to Capital Medical University after graduation, focusing on clinical and basic research in vascular surgery. This experience made me deeply appreciate the complexity and challenge of the field of vascular surgery, deepened my understanding of vascular surgical diseases, and strengthened my determination to continue on this path. During my master's degree, I had the honor to participate in the application work of the National Natural Science Foundation project, and carried out scientific research cooperation with the National Science Nano Center to jointly explore the application potential of nanotechnology in vascular surgery. I choose CIMR to pursue my doctoral degree because it brings together the top scientific research resources and first-class academic teams at home and abroad, providing a broad research platform and in-depth exchange opportunities for researchers. My research interests focus on the basic research of carotid artery and abdominal aortic diseases, and I firmly believe that I can obtain more systematic and in-depth scientific research training here, closely combine my clinical knowledge with scientific research interests, and make contributions to solving major scientific problems facing the field of vascular surgery. Looking forward to the future, I hope to promote the cutting-edge progress in the field of vascular surgery, and make my own contribution to improving the diagnosis and treatment level of vascular surgery in China and even in the world. The objective I aim to achieve in the coming decade is to become a proficient physician who excels in scientific research and demonstrates expertise in clinical technology. Moreover, I aspire to establish a seamless connection between innovative scientific research and practical clinical application, ultimately benefiting patients.