Education&Training
Graduate

Chinese Institutes for Medical Research (CIMR), Beijing(首都医学科学创新中心)is a research organization dedicated to advancing basic and translational medical research. Our goal is to tackle fundamental problems in human health with cutting edge technology and through inter-disciplinary collaborations with world-class scientists and physicians in Beijing. CIMR will provide education and training opportunities for future medical scientists. We are committed to a science-centered framework to promote innovation in research and education through a variety of novel funding mechanisms. CIMR provides graduate education programs in collaboration with Capital Medical University.

Q&A
1. For admissions, which universities are collaborating with CIMR?

The CIMR collaborates with Capital Medical University for the joint admission of doctoral candidates.

 

2. What are the admission methods available at the CIMR?
  • For Master’s degree candidates, there is an Application Assessment System for regular Ph.D. students.
  • For current undergraduate students, there is a Non-Examination Recommendation System for direct Ph.D. candidates.

 

3. Application Assessment System V.S. Non-Examination Recommendation System

 

  • Application Assessment System

Admission Targets: Fresh or former Master’s degree graduates

Timeline: Generally, the admission brochure is released between October and November each year, comprehensive assessments take place from December to April of the following year. Additional admission batches may be arranged annually based on the school’s unified enrollment schedule, with relevant information expected to be released around May. Students who pass the interview must obtain their Master’s degree and diploma, and they will start their Ph.D. studies in September of the following year.

 

  • Non-examination Recommendation System (Summer Camp)

Admission Targets: Fresh undergraduate students who qualify for the school’s recommendation.

Timeline: Generally, the admission brochure is released between April and May each year. Undergraduates in their junior year (or the fourth year for five-year programs) can apply and submit required materials as specified. Interviews usually take place in July, with the exact timing subject to annual variations. Students who pass the interview and receive the school’s recommendation must complete the National Recommendation System procedures and submit materials by September or October for admission in the following September.

 

No.

University

Admission Methods

Admission Targets

Time of releasing Admission Brochure

1

Capital Medical University (CMU)

Non-Examination Recommendation System

Fresh undergraduate students who qualify for the school’s recommendation

Between April and May

Application Assessment System

Fresh or former Master’s degree graduates

Between October and November

Additional admission batches for Application Assessment System

 

 

 

4. How to choose?
 

Capital Medical University (CMU)

The Chinese Institutes for Medical Research, Beijing (CIMR)

Neurobiology;

Immunology;

Pharmacology;

Biochemistry and Molecular Biology;

 

5. Where does the enrolled student’s status belong? Which school issues the diploma?

The student status belongs to Capital Medical University, and the diploma and degree are issued by Capital Medical University after graduation.

 

6. What professional background should students who want to apply have?

Students with a strong interest in the biological sciences are encouraged to apply. Applicants should have a background in biology, computer science, mathematics, physics, chemistry, medicine, materials, electronics, and other STEM areas. They should be enthusiastic about interdisciplinary academic research and be eager to participate in scientific research.

 

7. Do applicants need to contact mentors before applying?

There is no need to contact mentors in advance. Each mentor has a certain number of admission quotas each year, and if there is an interested mentor, you can apply directly. The CIMR implements a rotation system, and only admitted (or prospective) students need to contact mentors for rotation.

 

8. How many years is the length of schooling at CIMR?

Refer to the admissions brochure for the specific year.

  • Application Assessment System for general doctoral students (starting from master’s level)

Capital Medical University: 3-5 years.

  • Non-examination Recommendation System for direct doctoral students (starting from undergraduate level)

Capital Medical University: Generally 5-7 years, exceptionally outstanding students 3-4 years (no minimum requirements).

 

9. What are the advantages of admissions at CIMR?
  • The most prestigious and worldwide mentor team:The CIMR mentors are the most competent and influential young scientists recruited from abroad, including a significant number of non-Chinese international scientists. They have the most extensive research skills, the most committed research zeal, the widest vision, and the most promising development prospects.
  • Multidisciplinary background, fully cross-disciplinary, and open-sharing research atmosphere:We have top scientists from the United States, Europe, and around the world, students with diverse backgrounds in biology, chemistry, physics, mathematics, computer science, biotechnology, and clinical applications, as well as technical platforms, sample libraries, databases, and clinical case resource sharing systems jointly established by multiple units.
  • Innovative medical research talent training model: The CIMR collaborates closely with Capital Medical University (CMU) and more than 20 affiliated CMU hospitals, providing rich clinical research resources. It conducts basic medical research and clinical translational research centered on clinical problems.
  • Sufficient research funding:Mentors do not need to spend too much time applying for projects; most of their time can be used for research and guiding graduate students.
  • Complete supporting equipment: The CIMR’s technical support platform will purchase experimental equipment and devices according to the laboratory's needs, providing the most complete experimental facilities for the laboratory.
  • The best student treatment:Compared to other research institutes, the subsidies for students at the CIMR are significantly advantageous. Students can focus on research without worries.

 

10. Can students apply for admission to multiple schools’ admission projects simultaneously? How to submit application materials?

Applicants should carefully read the requirements of the corresponding admission projects, and then submit application materials according to the school’s admissions brochure and the CIMR’s supplementary requirements.

 

11. Is accommodation and transportation reimbursement arranged for students participating in interviews?

Offline interviews: The CIMR reimburses partial transportation expenses and covers all accommodation expenses for all students participating in interviews. In special cases, online interviews may be conducted.

 

12. How are doctoral students admitted to the CIMR allocated mentors? Is it necessary to contact mentors in advance?

Doctoral students at the CIMR must participate in three rounds of laboratory rotations, each lasting 1-3 months. Students need to contact mentors to determine rotation-related matters before confirming admission to the first year. We encourage students to interview with mentors to determine whether the laboratory can accept rotation, the rotation time, and the planned research project. After completing three rotation rounds, students are admitted through mutual selection between mentors and students.

We encourage students who have passed the second interview to start rotating in the CIMR before enrollment, which can effectively save time after enrollment. The early rotation can be in the form of an internship or graduation design. Early rotation helps students choose the laboratory they like.

 

13. What academic exchange activities does the CIMR have?

The CIMR’s academic activities are rich and diverse, including series of lectures such as:

  • PI Candidate Series Lectures
  • Invited Academic Lectures
  • Specific Topic Series Lectures
  • Internal Academic Exchange Series Lectures
  • In addition to the above lecture series, there are international academic conferences, research progress reports, and other academic exchange activities. Students at the CIMR not only benefit from exchanges and cooperation between laboratories within the institute or domestic laboratories but also exercise their abilities through face-to-face exchanges with top international peers.

 

14. What courses does the CIMR have?

After doctoral students enroll, they need to complete the courses required by the university’s training program and earn the required credits. The CIMR also offers special courses based on specific situations.

 

15. What are the graduation requirements for students at the CIMR?

The graduation requirements for students at the CIMR follow the requirements of the academic unit where their student status is located, and the CIMR does not impose additional requirements.

 

16. What forms of scholarships does the CIMR have?

All students studying at the CIMR, in addition to applying for scholarships established by the academic unit, can also apply for the “Doctoral Graduate Scholarship” established by the CIMR.

 

17. Besides research, what extracurricular activities does the CIMR have?

CIMR is preparing to establish a student union to enrich students' extracurricular lives, which will organize various cultural and sports activities, including outings, fun sports meetings, and teacher-student exchange meetings.

 

18. How is the treatment of students at the CIMR?
  • In addition to receiving living allowances and scholarships from the corresponding university, the CIMR also provides additional living allowances, increasing year by year.
  • The CIMR also sets up part-time work-study positions to help students alleviate economic pressure.
  • The CIMR also provides a certain amount of book purchase allowances.
  • Participation in rich academic and team-building recreational activities.
  • Many opportunities to interact with research experts in related fields internationally, including seminars, special reports, luncheons, and other forms.

 

19. What transportation options are available?
  • Shuttle bus: Shuttle buses from student dormitories to Capital Medical University.
  • Metro: West Tieying Station.

 

20. What should students do for medical treatment?

Students can seek emergency and outpatient care for illness at designated medical insurance hospitals nearby or go to hospitals affiliated with the academic unit. Medical insurance for students studying at the CIMR is implemented according to the requirements of the jointly recruiting schools.

 

21. What training courses does the CIMR have? Who are they for?

The CIMR holds winter training courses in January and summer training courses in July each year, targeting undergraduate and master’s students from various universities.

 

22. What is the relationship between training courses and admissions at the CIMR?

Training courses only involve material screening and do not include interview assessments, so they are not part of the admissions process. Admissions involve material screening and interview assessments, leading to the final selection of prospective students. Students who have attended training courses can apply for admission to the CIMR. Participating in CIMR training courses helps students understand the research direction and mentors of the center in advance.

 

23. How to apply for training courses?

In November and December each year and May and June each year, the CIMR’s official website will announce training course enrollment notices. Interested students can submit relevant materials according to the requirements of the brochure. The CIMR will organize an expert group to screen and select the best candidates, and the list will be announced on the CIMR’s official website.

 

24. What is the content of the training courses?

Through short-term courses, visits, team-building exchanges, short-term learning in laboratories, etc., students are encouraged to understand various research directions, current status, and cutting-edge advances in neuroscience. Students also preliminarily learn and master basic neuroscience experimental skills, enhance scientific thinking and expression abilities, and lay the foundation for future scientific research.

 

25. Are there fees for students participating in training courses? Is accommodation and transportation reimbursement arranged?

Training courses do not charge any training fees to students, and for offline courses, the CIMR reimburses partial transportation expenses and covers all accommodation expenses.

 

26. How can one learn more about CIMR?

Contact: Mr. Duan

Phone: 010-83950568

Email: education@cimrbj.ac.cn

 

 

Enrollment Calendar
Exemption: July and September every year;
Application for assessment: November each year and April of the following year.
Mentors More
Deguang LIANG
Assistant Investigator
Dr. Deguang Liang received his bachelor’s degree in Pharmaceutical Sciences from Sun Yat-sen University, and his Ph.D. in Microbiology from Institut Pasteur of Shanghai, Chinese Academy of Sciences. He conducted his postdoctoral research with Dr. Xuejun Jiang at Memorial Sloan Kettering Cancer Center. He will join CIMR as assistant investigator in 2024. His previous studies have been published in prestigious journals such as Cell, Molecular Cell, and Cell Research, among others.   Dr. Liang’s lab is dedicated to studying the molecular regulation and biological function of phospholipid (PL) metabolism pathways (e.g., PL de novo synthesis, remodeling, transport, etc.) under different physiological and pathological conditions. PLs are major components of cell membranes, and the dynamic changes in PL composition, on the one hand, regulate the physicochemical properties of cell membranes and influence cellular functions (such as cell migration, phagocytosis, exocytosis, autophagy, mitochondrial aerobic respiration, etc.). On the other hand, they also modulate the sensitivity of cells to ferroptosis (an emerging form of regulated cell death caused by iron-mediated PL peroxidation) and affect the occurrence and progression of related diseases (such as tumors, neurodegenerative diseases, ischemia-reperfusion injury, etc.). Therefore, investigating the intricate feedback regulation of cellular PL metabolism pathways holds significant importance for both basic and translational research.
Details
Lin MEI
Distinguished Investigator
Dr. Lin Mei pioneered our apprehension of the development and function of synapses - nerve cell contacts critical to the communication between neurons. He revealed molecular mechanisms of the formation of the neuromuscular junction (NMJ), a special synapse critical to our mobility. He discovered that LRP4, a molecule critical to NMJ formation, serves as the receptor for agrin, solving a decade-old mystery. By solving the crystal structure of an agrin-LRP4 complex, he revealed how signal is transduced from agrin to the downstream kinase MuSK. Dr. Mei also uncovered LRP4 antibodies as a new biomarker for myasthenia gravis that otherwise cannot be diagnosed. He recently revealed rapsyn, a classic “adapter protein”, undergoes phase condensation and is in fact an enzyme whose activity is necessary for NMJ formation, uncovering brand-new mechanisms. Dr. Mei has also discovered an important homeostatic control of brain activity by neuregulin 1 and its receptor ErbB4, both risk genes of major depression and schizophrenia. Dr. Mei’s paradigm-shifting works have been described in neuroscience textbooks and have an enormous impact on clinical practice. For example, a test he invented to detect LRP4 antibodies has been used worldwide in the clinic to diagnose myasthenia gravis. Dr. Mei led a consortium of seventeen clinical centers in the US to study newly identified biomarkers in myasthenia gravis. Many of his trainees including 12 PhD students have become independent scientists.         Dr. Mei is currently the founding Director, Chinese Institutes for Medical Research, Beijing. In 2017-2023, he was the Chair, Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio and the founding Director of Cleveland Brain Health Initiative that brings together the collaborative expertise of ~500 scientists and clinicians in Cleveland to improve brain health. Earlier, he was on faculty at the University of Virginia, University of Alabama at Birmingham, and Medical College of Georgia where he established a new Department of Neuroscience and Regenerative Medicine.   
Details
Xu TAN
Investigator 
Professor Xu Tan obtained his bachelor’s and Ph.D. degrees from the University of Science and Technology of China and the University of Washington in Seattle, respectively. During graduate school, he worked with Dr. Ning Zheng and identified the first molecular glue degrader. He conducted postdoctoral research on genetics and virology with Dr. Stephen Elledge at Harvard Medical School. From 2014 to 2023, he ran his own laboratory at Tsinghua University before joining the CIMR in 2023. His lab conducts studies on virus-host interactions and antiviral drug discovery using high-throughput screening technologies for SARS-CoV2, HIV, hepatitis B, and Zika viruses. Professor Tan has first-author and corresponding-author publications in high-impact journals such as Nature, Nature Genetics, Nature Biotechnology, Nature Microbiology, Cell Host & Microbe, Cell Research, Nature Communications, and PNAS, which have been cited over 6000 times. He has led an international cooperation project and two sub-projects of the Ministry of Science and Technology’s Key Research and Development Program. He has also won grants of the National Natural Science Foundation’s Excellent Young Scientist and General Programs. For his scientific accomplishments, Dr. Tan was awarded the Bayer Investigator Award, the Damon Runyon Postdoctoral Fellowship, the  GE and Science Magazine Young Life Scientist Award etc. His lab has generated several national and international patents.
Details
PhD. Students More

Chinese Institutes for Medical Research (CIMR), Beijing(首都医学科学创新中心)is a research organization dedicated to advancing basic and translational medical research. Our goal is to tackle fundamental problems in human health with cutting edge technology and through inter-disciplinary collaborations with world-class scientists and physicians in Beijing. CIMR will provide education and training opportunities for future medical scientists. We are committed to a science-centered framework to promote innovation in research and education through a variety of novel funding mechanisms. CIMR provides graduate education programs in collaboration with Capital Medical University.

Q&A
1. For admissions, which universities are collaborating with CIMR?

The CIMR collaborates with Capital Medical University for the joint admission of doctoral candidates.

 

2. What are the admission methods available at the CIMR?
  • For Master’s degree candidates, there is an Application Assessment System for regular Ph.D. students.
  • For current undergraduate students, there is a Non-Examination Recommendation System for direct Ph.D. candidates.

 

3. Application Assessment System V.S. Non-Examination Recommendation System

 

  • Application Assessment System

Admission Targets: Fresh or former Master’s degree graduates

Timeline: Generally, the admission brochure is released between October and November each year, comprehensive assessments take place from December to April of the following year. Additional admission batches may be arranged annually based on the school’s unified enrollment schedule, with relevant information expected to be released around May. Students who pass the interview must obtain their Master’s degree and diploma, and they will start their Ph.D. studies in September of the following year.

 

  • Non-examination Recommendation System (Summer Camp)

Admission Targets: Fresh undergraduate students who qualify for the school’s recommendation.

Timeline: Generally, the admission brochure is released between April and May each year. Undergraduates in their junior year (or the fourth year for five-year programs) can apply and submit required materials as specified. Interviews usually take place in July, with the exact timing subject to annual variations. Students who pass the interview and receive the school’s recommendation must complete the National Recommendation System procedures and submit materials by September or October for admission in the following September.

 

No.

University

Admission Methods

Admission Targets

Time of releasing Admission Brochure

1

Capital Medical University (CMU)

Non-Examination Recommendation System

Fresh undergraduate students who qualify for the school’s recommendation

Between April and May

Application Assessment System

Fresh or former Master’s degree graduates

Between October and November

Additional admission batches for Application Assessment System

 

 

 

4. How to choose?
 

Capital Medical University (CMU)

The Chinese Institutes for Medical Research, Beijing (CIMR)

Neurobiology;

Immunology;

Pharmacology;

Biochemistry and Molecular Biology;

 

5. Where does the enrolled student’s status belong? Which school issues the diploma?

The student status belongs to Capital Medical University, and the diploma and degree are issued by Capital Medical University after graduation.

 

6. What professional background should students who want to apply have?

Students with a strong interest in the biological sciences are encouraged to apply. Applicants should have a background in biology, computer science, mathematics, physics, chemistry, medicine, materials, electronics, and other STEM areas. They should be enthusiastic about interdisciplinary academic research and be eager to participate in scientific research.

 

7. Do applicants need to contact mentors before applying?

There is no need to contact mentors in advance. Each mentor has a certain number of admission quotas each year, and if there is an interested mentor, you can apply directly. The CIMR implements a rotation system, and only admitted (or prospective) students need to contact mentors for rotation.

 

8. How many years is the length of schooling at CIMR?

Refer to the admissions brochure for the specific year.

  • Application Assessment System for general doctoral students (starting from master’s level)

Capital Medical University: 3-5 years.

  • Non-examination Recommendation System for direct doctoral students (starting from undergraduate level)

Capital Medical University: Generally 5-7 years, exceptionally outstanding students 3-4 years (no minimum requirements).

 

9. What are the advantages of admissions at CIMR?
  • The most prestigious and worldwide mentor team:The CIMR mentors are the most competent and influential young scientists recruited from abroad, including a significant number of non-Chinese international scientists. They have the most extensive research skills, the most committed research zeal, the widest vision, and the most promising development prospects.
  • Multidisciplinary background, fully cross-disciplinary, and open-sharing research atmosphere:We have top scientists from the United States, Europe, and around the world, students with diverse backgrounds in biology, chemistry, physics, mathematics, computer science, biotechnology, and clinical applications, as well as technical platforms, sample libraries, databases, and clinical case resource sharing systems jointly established by multiple units.
  • Innovative medical research talent training model: The CIMR collaborates closely with Capital Medical University (CMU) and more than 20 affiliated CMU hospitals, providing rich clinical research resources. It conducts basic medical research and clinical translational research centered on clinical problems.
  • Sufficient research funding:Mentors do not need to spend too much time applying for projects; most of their time can be used for research and guiding graduate students.
  • Complete supporting equipment: The CIMR’s technical support platform will purchase experimental equipment and devices according to the laboratory's needs, providing the most complete experimental facilities for the laboratory.
  • The best student treatment:Compared to other research institutes, the subsidies for students at the CIMR are significantly advantageous. Students can focus on research without worries.

 

10. Can students apply for admission to multiple schools’ admission projects simultaneously? How to submit application materials?

Applicants should carefully read the requirements of the corresponding admission projects, and then submit application materials according to the school’s admissions brochure and the CIMR’s supplementary requirements.

 

11. Is accommodation and transportation reimbursement arranged for students participating in interviews?

Offline interviews: The CIMR reimburses partial transportation expenses and covers all accommodation expenses for all students participating in interviews. In special cases, online interviews may be conducted.

 

12. How are doctoral students admitted to the CIMR allocated mentors? Is it necessary to contact mentors in advance?

Doctoral students at the CIMR must participate in three rounds of laboratory rotations, each lasting 1-3 months. Students need to contact mentors to determine rotation-related matters before confirming admission to the first year. We encourage students to interview with mentors to determine whether the laboratory can accept rotation, the rotation time, and the planned research project. After completing three rotation rounds, students are admitted through mutual selection between mentors and students.

We encourage students who have passed the second interview to start rotating in the CIMR before enrollment, which can effectively save time after enrollment. The early rotation can be in the form of an internship or graduation design. Early rotation helps students choose the laboratory they like.

 

13. What academic exchange activities does the CIMR have?

The CIMR’s academic activities are rich and diverse, including series of lectures such as:

  • PI Candidate Series Lectures
  • Invited Academic Lectures
  • Specific Topic Series Lectures
  • Internal Academic Exchange Series Lectures
  • In addition to the above lecture series, there are international academic conferences, research progress reports, and other academic exchange activities. Students at the CIMR not only benefit from exchanges and cooperation between laboratories within the institute or domestic laboratories but also exercise their abilities through face-to-face exchanges with top international peers.

 

14. What courses does the CIMR have?

After doctoral students enroll, they need to complete the courses required by the university’s training program and earn the required credits. The CIMR also offers special courses based on specific situations.

 

15. What are the graduation requirements for students at the CIMR?

The graduation requirements for students at the CIMR follow the requirements of the academic unit where their student status is located, and the CIMR does not impose additional requirements.

 

16. What forms of scholarships does the CIMR have?

All students studying at the CIMR, in addition to applying for scholarships established by the academic unit, can also apply for the “Doctoral Graduate Scholarship” established by the CIMR.

 

17. Besides research, what extracurricular activities does the CIMR have?

CIMR is preparing to establish a student union to enrich students' extracurricular lives, which will organize various cultural and sports activities, including outings, fun sports meetings, and teacher-student exchange meetings.

 

18. How is the treatment of students at the CIMR?
  • In addition to receiving living allowances and scholarships from the corresponding university, the CIMR also provides additional living allowances, increasing year by year.
  • The CIMR also sets up part-time work-study positions to help students alleviate economic pressure.
  • The CIMR also provides a certain amount of book purchase allowances.
  • Participation in rich academic and team-building recreational activities.
  • Many opportunities to interact with research experts in related fields internationally, including seminars, special reports, luncheons, and other forms.

 

19. What transportation options are available?
  • Shuttle bus: Shuttle buses from student dormitories to Capital Medical University.
  • Metro: West Tieying Station.

 

20. What should students do for medical treatment?

Students can seek emergency and outpatient care for illness at designated medical insurance hospitals nearby or go to hospitals affiliated with the academic unit. Medical insurance for students studying at the CIMR is implemented according to the requirements of the jointly recruiting schools.

 

21. What training courses does the CIMR have? Who are they for?

The CIMR holds winter training courses in January and summer training courses in July each year, targeting undergraduate and master’s students from various universities.

 

22. What is the relationship between training courses and admissions at the CIMR?

Training courses only involve material screening and do not include interview assessments, so they are not part of the admissions process. Admissions involve material screening and interview assessments, leading to the final selection of prospective students. Students who have attended training courses can apply for admission to the CIMR. Participating in CIMR training courses helps students understand the research direction and mentors of the center in advance.

 

23. How to apply for training courses?

In November and December each year and May and June each year, the CIMR’s official website will announce training course enrollment notices. Interested students can submit relevant materials according to the requirements of the brochure. The CIMR will organize an expert group to screen and select the best candidates, and the list will be announced on the CIMR’s official website.

 

24. What is the content of the training courses?

Through short-term courses, visits, team-building exchanges, short-term learning in laboratories, etc., students are encouraged to understand various research directions, current status, and cutting-edge advances in neuroscience. Students also preliminarily learn and master basic neuroscience experimental skills, enhance scientific thinking and expression abilities, and lay the foundation for future scientific research.

 

25. Are there fees for students participating in training courses? Is accommodation and transportation reimbursement arranged?

Training courses do not charge any training fees to students, and for offline courses, the CIMR reimburses partial transportation expenses and covers all accommodation expenses.

 

26. How can one learn more about CIMR?

Contact: Mr. Duan

Phone: 010-83950568

Email: education@cimrbj.ac.cn

 

 

Enrollment Calendar
Exemption: July and September every year;
Application for assessment: November each year and April of the following year.
Mentors
Deguang LIANG
Assistant Investigator
Dr. Deguang Liang received his bachelor’s degree in Pharmaceutical Sciences from Sun Yat-sen University, and his Ph.D. in Microbiology from Institut Pasteur of Shanghai, Chinese Academy of Sciences. He conducted his postdoctoral research with Dr. Xuejun Jiang at Memorial Sloan Kettering Cancer Center. He will join CIMR as assistant investigator in 2024. His previous studies have been published in prestigious journals such as Cell, Molecular Cell, and Cell Research, among others.   Dr. Liang’s lab is dedicated to studying the molecular regulation and biological function of phospholipid (PL) metabolism pathways (e.g., PL de novo synthesis, remodeling, transport, etc.) under different physiological and pathological conditions. PLs are major components of cell membranes, and the dynamic changes in PL composition, on the one hand, regulate the physicochemical properties of cell membranes and influence cellular functions (such as cell migration, phagocytosis, exocytosis, autophagy, mitochondrial aerobic respiration, etc.). On the other hand, they also modulate the sensitivity of cells to ferroptosis (an emerging form of regulated cell death caused by iron-mediated PL peroxidation) and affect the occurrence and progression of related diseases (such as tumors, neurodegenerative diseases, ischemia-reperfusion injury, etc.). Therefore, investigating the intricate feedback regulation of cellular PL metabolism pathways holds significant importance for both basic and translational research.
Lin MEI
Distinguished Investigator
Dr. Lin Mei pioneered our apprehension of the development and function of synapses - nerve cell contacts critical to the communication between neurons. He revealed molecular mechanisms of the formation of the neuromuscular junction (NMJ), a special synapse critical to our mobility. He discovered that LRP4, a molecule critical to NMJ formation, serves as the receptor for agrin, solving a decade-old mystery. By solving the crystal structure of an agrin-LRP4 complex, he revealed how signal is transduced from agrin to the downstream kinase MuSK. Dr. Mei also uncovered LRP4 antibodies as a new biomarker for myasthenia gravis that otherwise cannot be diagnosed. He recently revealed rapsyn, a classic “adapter protein”, undergoes phase condensation and is in fact an enzyme whose activity is necessary for NMJ formation, uncovering brand-new mechanisms. Dr. Mei has also discovered an important homeostatic control of brain activity by neuregulin 1 and its receptor ErbB4, both risk genes of major depression and schizophrenia. Dr. Mei’s paradigm-shifting works have been described in neuroscience textbooks and have an enormous impact on clinical practice. For example, a test he invented to detect LRP4 antibodies has been used worldwide in the clinic to diagnose myasthenia gravis. Dr. Mei led a consortium of seventeen clinical centers in the US to study newly identified biomarkers in myasthenia gravis. Many of his trainees including 12 PhD students have become independent scientists.         Dr. Mei is currently the founding Director, Chinese Institutes for Medical Research, Beijing. In 2017-2023, he was the Chair, Department of Neurosciences, Case Western Reserve University, Cleveland, Ohio and the founding Director of Cleveland Brain Health Initiative that brings together the collaborative expertise of ~500 scientists and clinicians in Cleveland to improve brain health. Earlier, he was on faculty at the University of Virginia, University of Alabama at Birmingham, and Medical College of Georgia where he established a new Department of Neuroscience and Regenerative Medicine.   
Xu TAN
Investigator 
Professor Xu Tan obtained his bachelor’s and Ph.D. degrees from the University of Science and Technology of China and the University of Washington in Seattle, respectively. During graduate school, he worked with Dr. Ning Zheng and identified the first molecular glue degrader. He conducted postdoctoral research on genetics and virology with Dr. Stephen Elledge at Harvard Medical School. From 2014 to 2023, he ran his own laboratory at Tsinghua University before joining the CIMR in 2023. His lab conducts studies on virus-host interactions and antiviral drug discovery using high-throughput screening technologies for SARS-CoV2, HIV, hepatitis B, and Zika viruses. Professor Tan has first-author and corresponding-author publications in high-impact journals such as Nature, Nature Genetics, Nature Biotechnology, Nature Microbiology, Cell Host & Microbe, Cell Research, Nature Communications, and PNAS, which have been cited over 6000 times. He has led an international cooperation project and two sub-projects of the Ministry of Science and Technology’s Key Research and Development Program. He has also won grants of the National Natural Science Foundation’s Excellent Young Scientist and General Programs. For his scientific accomplishments, Dr. Tan was awarded the Bayer Investigator Award, the Damon Runyon Postdoctoral Fellowship, the  GE and Science Magazine Young Life Scientist Award etc. His lab has generated several national and international patents.
Honghu ZHU
Associate Investigator
Professor Hong-Hu Zhu got his Ph.D. from Peking University under the supervision of Professor Daopei Lu, an academician of the Chinese Academy of Engineering. He is a member of the International Acute Promyelocytic Leukemia (APL) Foundation, a member of the Asia‐Pacific Leukemia Consortium, a standing committee member of the Hematology-Oncology Committee of the Chinese Anti-Cancer Association, an executive committee member of the China Association of Chinese Medicine Blood Disease Branch, a committee member of the Leukemia and Lymphoma Group of Chinese Society of Hematology in Chinese Medical Association, and the deputy director of the Cell Analysis Committee, Chinese Society of Biotechnology.   Professor Zhu has worked in hematology for 29 years, specializing in clinical and translational research in acute leukemia. His primary academic achievements include:   First, establishing a unique chemo-free outpatient treatment model with oral arsenics ad ATRA for acute promyelocytic leukemia (APL), with a cure rate of more than 95%.【J Clin Oncol(2013)、N Eng J Med(2014a,2014b)、Lancet Oncol(2018)、Blood(2016, 2018, 2019),J Hematol Oncol(2022)】   Second, establishing the DAV (daunorubicin, cytarabine, and homoharringtonine) regimen as front-line treatment for newly diagnosed acute myeloid leukemia (AML), with a complete remission  rate exceeding 90%.【Lancet Haematol 2022】   Third, Pioneering the definition of a new subtype of leukemia, RARG rearranged AML for the first time internationally.【Leukemia 2018、Leuk Res 2019, Blood Advance 2023】   Professor Zhu is at the forefront of developing efficient, low-toxicity leukemia treatment procedures and tailored diagnostic and therapeutic approaches in China. 
PhD. Students
Jihao ZHENG
Ph.D. Candidate, Class of 2024   I obtained my Master's degree from South China Agricultural University, where I focused primarily on vaccine research for viral infectious diseases in animals. During my master's programme, I developed a probiotic oral vaccine for the prevention of Porcine Epidemic Diarrhea Virus (PEDV). This probiotic vaccine addressed the shortcomings of traditional vaccines in terms of immunological persistence, gut microbiota balance, and safety, demonstrating the potential of oral vaccines in practical applications. After graduation, I underwent a year of training in the JayYu Lab at the Guangzhou National Laboratory, where my research mainly concentrated on vaccine and gene therapy tool development based on viral vectors.   Throughout millions of years of human struggle against viruses, we have evolved complex and diverse immune mechanisms to combat viral invasion. Meanwhile, viruses continuously mutate and evolve to evade host immune responses, creating a subtle "competition" between viruses and their hosts. This intricate process involves numerous deep mechanisms and dynamic changes, reflecting the complexity of biological systems and providing us with a vast field for exploration. As Sun Tzu said in The Art of War: "Know thy enemy and know thyself, and you can fight a hundred battles without disaster." I have a profound interest in the study of viral infection and host immunity, and I hope to gain a better understanding of the processes of viral infection and host immune responses through in-depth research into these subtle biological processes, and to truly gain the wisdom of knowing both the enemy and ourselves in order to face future viral challenges.   I chose to pursue my Ph.D. at the CIMR because it brings together world-class scientists and their research teams, offering exceptional scientific resources, advanced research facilities, and a rich research atmosphere. I want to conduct scientific research in this free, open, inclusive, and transparent environment, which will allow me to delve deeper into the mechanisms of viral infection and immune processes, solve current research challenges, and lay a solid foundation for future endeavors.     I hope that in ten years's time, I will have made significant contributions to the field of virology while remaining passionate about scientific research.
Shuqin JI
Ph.D. Candidate, Class of 2024   I graduated from Xinxiang Medical University with a bachelor's degree in Clinical Medicine (Physician Education and Training Programme of Excellence). Subsequently, I pursued and obtained my master's degree in Pathology at Chongqing Medical University. During my postgraduate studies, I immersed myself in scientific research at the Center for Molecular Medicine and Oncology Research, focusing on identifying novel cancer biomarkers and investigating their role in cancer pathogenesis. Additionally, I served as a research assistant at the Brain and Intelligence Research Key Laboratory of the Chongqing Education Commission, affiliated to the Third Military Medical University.   The Chinese Institutes for Medical Research (CIMR), Beijing is dedicated to advancing medical science and improving human health through groundbreaking biomedical research. CIMR is committed to strengthening the innovation and translational capabilities of medical science and raising the standards of disease diagnosis and treatment. The Institute brings together a community of world-class scientists and their research teams, and collaborates closely with Beijing's premier medical education and scientific research resources. Together, we foster a multidisciplinary research environment that nurtures a new paradigm of scientific exploration, drives the integration of medicine, education, research, and industry, and cultivates top-tier talent poised to lead in the era of medical innovation. I am deeply honored to continue my scientific exploration on this prestigious platform.   The advent of high-throughput sequencing, single-cell sequencing, and bioinformatics has revolutionized our understanding of the immune system's intricate network, shedding light on the interactions among immune cells and the mechanisms underlying immune regulation. These advancements hold immense potential for scientific discovery and for advancing human health and disease management. In particular, cancer therapy remains a formidable challenge, with the complexity of tumor immune microenvironments and the quest for novel immunotherapeutic targets at the forefront. I aim to leverage single-cell transcriptome sequencing to map cellular dynamics within tumor microenvironments, uncovering new subsets of macrophages and deepening our understanding of these complex systems. This work is essential for developing innovative immunotherapeutic strategies. Furthermore, I am eager to explore the immune system's pivotal role in various disease pathogeneses and treatments, and to contribute to the discovery of groundbreaking therapeutic approaches.   I aspire to be a catalyst for discovery, driven by a spirit of exploration and a commitment to making a tangible impact through research. I will maintain an unwavering curiosity and inquisitiveness, coupled with a rigorous and meticulous approach to my work. A decade from now, I envision myself as a respected immunology researcher, having achieved significant milestones, tackling key scientific questions, and seeing my research findings translated into clinical practice, thereby contributing positively to the fields of life sciences and clinical medicine. I also hope to become an exemplary mentor, guiding and inspiring a new generation of scientists to pursue their academic aspirations with passion and dedication. Above all, I will continue to cherish life's passions and the joy of unraveling life's mysteries, with enduring vigor and love in my heart.   From the steady dawn of each day, small yet significant strides, like the quiet accumulation of morning dew, will persist, and from this perseverance, brilliance and radiance shall emerge. 
Xinjie LI
Ph.D. Candidate, Class of 2024   I graduated from Hebei Medical University majoring in pharmacy and am now a PhD student in the CIMR.   As the forward position of scientific research and innovation, CIMR brings together top scientific research talents and rich academic resources at home and abroad. It not only has advanced experimental equipment and research platform, but also holds high-level academic seminars frequently. Choosing the CIMR to study for a doctorate means standing at the forefront of scientific research. Here I can explore unknown scientific problems with experts from different fields, which can not only inspire new research inspiration, but also cultivate my ability to solve complex problems and lay a solid foundation for my future scientific research career.   I am very interested in the research in the field of neuroscience, especially the transmission mechanism of neural signals, neural plasticity and their mechanism in the process of learning and memory. In addition, I have unlimited expectations for the potential application of neuroscience in the field of artificial intelligence, and dream of learning from the excellent working way of the brain to develop more advanced and efficient algorithms and computational models.   Looking forward to the next decade, I look forward to growing into an influential researcher in the field of neuroscience. I am eager to leave my footprint in the academic palace, not only publishing a number of high-quality research papers with far-reaching impact in top academic journals, but also leaving my name in the frontier exploration of neuroscience. I dream of participating in or leading a series of landmark research projects that can not only deepen our understanding of neural mechanisms, but also inject new vitality into the development of artificial intelligence. promote cross-integration and common progress in the two fields.
Yunlei WEI
Ph.D. Candidate, Class of 2024   I completed both my bachelor's and master's degrees at the School of Medicine, Anhui University of Science and Technology, where my master's research focused on the prevention of postoperative esophageal stricture. Through my years of study and research, I have gained a deep understanding of the complexity and challenges in the medical field.   I learned that the Chinese Institutes for Medical Research is a cutting-edge, multidisciplinary research platform with highly skilled scientists and outstanding research teams. The center also collaborates closely with top-tier medical education and research resources in the capital, which fills me with great anticipation and admiration. Such an environment not only fosters scientific innovation but also provides valuable support and resources for my academic growth.    During my PhD studies, I aim to maintain a rigorous and diligent approach to learning, steadily advancing my research, and continuously accumulating knowledge and skills to achieve both theoretical and practical breakthroughs. I am particularly interested in the mechanisms of the immune system's role in diseases such as cancer, specifically how it functions in the occurrence and treatment of these diseases. I hope to gain a deeper understanding of the immune system's responses and regulatory mechanisms in various pathological conditions through basic research. Based on this, I aspire to discover ways to harness the immune system's potential, advancing the application of immunotherapy in disease treatment, and ultimately contributing to human health.   Looking ahead, I envision myself, in ten years, having made significant progress in the field of tumor immunology, establishing myself as a specialized researcher in this area. I hope to lead my own research team, continually driving breakthrough advancements and contributing to the forefront of medical research on the international stage. At the same time, I hope that my research will tangibly benefit patients, helping more people overcome disease, and realizing the goal of "academic research serving human health". 
Jiajun YANG
Ph.D. Candidate, Class of 2024   I completed both my bachelor's and master's degrees in Stomatology at Sun Yat-sen University, following a 5+3 academic system. During my master's program, I underwent Standardized Residents Training at Hospital of Stomatology, Sun Yat-sen University, where I also engaged in research focused on the physicochemical properties of dental restorative materials.   After graduation, I worked as a dentist in oral diagnosis and treatment. Through this experience, I deeply felt the contradiction between patients' pursuit of health and the limitations of existing medical practices. This conflict reignited my passion for scientific research, prompting me to leave my clinical position and pursue a Ph.D. at CIMR. I hope to strengthen the connection between clinical and fundamental research to facilitate the translation of scientific discoveries into practical applications, ultimately benefiting more patients.   I am particularly interested in biochemistry and molecular biology, as they form a crucial foundation of life sciences. In the future, I aim to delve into the mechanisms of interactions among different molecular pathways during tumor onset, progression, and prognosis, seeking new breakthroughs for clinical cancer treatment. Throughout my studies at CIMR, I will strive to enhance my research skills and critical thinking. Regardless of my future career path, I will remain committed to the oath I took as a medical student: to dedicate my life to the health and well-being of humanity.
Minwei LI
Ph.D. Candidate, Class of 2024   I have a bachelor's degree from Chengdu University of Traditional Chinese Medicine and a master's degree from Wenzhou Medical University. During my master's degree, my research direction was the development of new methods for detection of infectious diseases. The main work is to develop a fast, convenient and efficient monitoring method for trace pathogens of bloodstream infection by transforming bacteriophages into probes using crisper technology and combining them with microfluidic chips. CIMR as one of the three major sectors of the development of Capital Medical University, before I came in, I tried to apply just because of the recommendation of my senior sister. But in retrospect, I'm glad I made that choice once. CIMR has a strong academic atmosphere, and the communication between teachers and students is particularly open (students are encouraged to question and criticize), which is rare among the colleges and research institutions I have come into contact with. The research group rotation mechanism also gives students the opportunity to learn more about the research direction and choose the topic that suits them. At the same time, the center also has a lot of academic activities, such as the forum and lunch meeting every Wednesday (having a meal with the report teacher) and Journal Club for students every Friday, which can constantly develop and train students' scientific research literacy. I think this is very attractive for students who want to improve their academic ability. One year after the establishment of CIMR, there are many attractive new highlights (high subsidies, adequate resources, open thinking, novel administrative mechanisms, etc.), but there are also many new services and new policies to be formulated and developed. Such as dormitories, rotations, student work, etc. (I don't know if I can say) but I believe that with such open tutors and administrative teachers, it is only a matter of time before these problems are solved. The future teachers and sisters will usher in a better CIMR. As for the scientific problems to be solved in the future, in a narrow sense, it is what the direction of the supervisor wants to solve; Broadly speaking, I hope to use the ability to discover problems, design experiments and solve problems cultivated during the years of doctoral study to solve current people's health problems. I will work hard and hope that 10 years later, my conscience is clear.
Cuidie WANG
Ph.D. Candidate, Class of 2024   I graduated from Hebei Medical University with a degree in Basic Medicine. During my undergraduate studies, my research internship focused on emotional respiratory regulation, and I participated in the national key project titled "Mechanisms of Respiratory Abnormalities Induced by Anxiety-like Behavior." This project centers on the neurobiological basis of respiratory changes induced by anxiety emotions and proposes for the first time that acute restraint stress models activate neurons in the central amygdala. By combining optogenetics with behavioral experiments and non-invasive volume plethysmography in small animals, I validated the role of the central amygdala in anxiety-like behaviors from multiple perspectives and explored how it induces respiratory changes through the regulation of the pre-Bötzinger complex, providing a theoretical basis for understanding the relationship between anxiety emotions and respiratory regulation.   For my graduation design project, I focused on "The Role of the Periventricular Nucleus in the Process of Extinction of Acute Stress-Related Anxiety-like Behaviors," investigating the neural circuit mechanisms of the periventricular nucleus in stress-related anxiety-like behaviors. Given that current clinical treatments for stress-related mental illnesses and their efficacy remain unsatisfactory, elucidating the brain mechanisms that trigger anxiety disorders due to stress is expected to provide potential directions for new treatment strategies.   CIMR features a multidisciplinary modern medical research system dedicated to establishing a goal-oriented research model centered on medicine, promoting the translation of basic research into clinical medical results. Collaborations with various hospitals allow research to be more closely aligned with clinical needs, facilitating the rapid translation of research outcomes, while a new management and research model lays the foundation for the center's long-term development.   I have a keen interest in the field of neurobiology. With the increasing social pressures, emotional problems are becoming more common, and neurobiology provides a foundation for understanding both animal and human behaviors. By studying how the nervous system affects emotions, learning, memory, and decision-making, we can delve into complex biological behaviors. Furthermore, understanding the mechanisms of neurobiology aids in the development of drugs for mental illnesses and offers theoretical support for addressing issues such as addiction, mental disorders, and social behavior abnormalities.   Currently, the diagnosis of various emotional disorders primarily relies on scale assessments, with few laboratory diagnostic methods available. Therefore, I hope to analyze neural network activities related to emotional disorders to identify potential biological markers for early diagnosis, predicting disease progression, and assessing treatment effectiveness. Additionally, in-depth research on neural networks can reveal differences in emotional responses and manifestations of emotional disorders among individuals, which is crucial for personalized medicine and precision treatment.   Through continuous research training, I aspire to achieve significant accomplishments in my chosen field, publish high-impact papers, and establish a reputation in academia and industry. I aim to combine interdisciplinary knowledge and methods to tackle complex scientific problems and drive research innovation. Most importantly, I will maintain a curiosity for new knowledge and technologies, embrace challenges, and continuously learn and improve to adapt to the rapidly evolving scientific landscape. 
Yida CAO
Ph.D. Candidate, Class of 2024   I began my academic journey in Capital Medical University and went on to pursue a master's degree in Beijing Anzhen Hospital affiliated to Capital Medical University after graduation, focusing on clinical and basic research in vascular surgery. This experience made me deeply appreciate the complexity and challenge of the field of vascular surgery, deepened my understanding of vascular surgical diseases, and strengthened my determination to continue on this path. During my master's degree, I had the honor to participate in the application work of the National Natural Science Foundation project, and carried out scientific research cooperation with the National Science Nano Center to jointly explore the application potential of nanotechnology in vascular surgery.   I choose CIMR to pursue my doctoral degree because it brings together the top scientific research resources and first-class academic teams at home and abroad, providing a broad research platform and in-depth exchange opportunities for researchers. My research interests focus on the basic research of carotid artery and abdominal aortic diseases, and I firmly believe that I can obtain more systematic and in-depth scientific research training here, closely combine my clinical knowledge with scientific research interests, and make contributions to solving major scientific problems facing the field of vascular surgery.   Looking forward to the future, I hope to promote the cutting-edge progress in the field of vascular surgery, and make my own contribution to improving the diagnosis and treatment level of vascular surgery in China and even in the world. The objective I aim to achieve in the coming decade is to become a proficient physician who excels in scientific research and demonstrates expertise in clinical technology. Moreover, I aspire to establish a seamless connection between innovative scientific research and practical clinical application, ultimately benefiting patients.
Lin ZHI
Ph.D. Candidate, Class of 2024   I completed my undergraduate studies at Jinan University and my master's degree at Sichuan University West China School of Clinical Medicine, focusing on the impact of novel hydrogels on flap survival and scar-related research. During my master's program, I honed my clinical skills as a specialized surgical (burns/plastic surgery) doctor and accumulated extensive research experience, which allowed me to master essential knowledge and techniques in the fields of burns and plastic surgery while cultivating a compassionate medical ethos.   I chose to pursue my PhD at the CIMR because it offers an outstanding research platform, advanced equipment, and a team of experienced mentors across various fields. I believe this environment will provide me with a broader research perspective and deeper research opportunities. My research interests include investigating the mechanisms of melanoma pathogenesis and exploring the microenvironment of chronic wounds and radiation ulcers, with the aim of unveiling their biological characteristics and potential therapeutic targets.   In the future, I hope to elucidate the mechanisms underlying malignant melanoma, identify early warning biomarkers, and develop more effective treatment strategies. Additionally, I am dedicated to improving the prognosis of patients with chronic wounds and radiation ulcers by promoting wound healing through microenvironment modulation. Ten years from now, I aspire to be an expert in the fields of melanoma and chronic wound research, possessing multiple clinically translatable research outcomes that drive progress in related areas. Ultimately, I aim to lead an excellent research and clinical team to provide new solutions for global plastic surgery-related diseases, particularly in wound healing and cancer treatment.