Majors for Enrollment: Neurology Neurobiology Biochemistry and Molecular Biology  B.S. in Biological Science, Tsinghua University, China M.S. in Biology, Tsinghua University, China Ph.D. in Biomedical and Pharmaceutical Sciences, Université catholique de Louvain, Belgium  2024.2-Present Assistant Investigator, Chinese Institutes for Medical Research, Beijing, China 2021.6-Present Professor and Principal Investigator, Xuanwu Hospital, Capital Medical University, China 2015.7-2021.5 Postdoc Scholar, University of California, San Diego, USA  The Chai laboratory at CIMR focuses on the forefront of genetic diagnosis and treatment of neurological disorders.

Majors for Enrollment: Genetics Immunology Biochemistry and Molecular Biology Pathogenic BiologyOncology Cell Biology B.S. in Biotechnology, Soochow University, ChinaPh.D. in Biochemistry & Molecular Biology, Shanghai Jiao Tong University School of Medicine, China 2025-PresentAssistant Investigator, Chinese Institutes for Medical Research, Beijing, China2017-2024Research Scientist/Instructor, The University of Texas MD Anderson Cancer Center, Texas, USA2014-2017Postdoctoral Associate, Baylor College of Medicine, Texas, USA2009-2014Postdoctoral Fellow/Research Associate, Chinese National Human Genome Center at Shanghai, Shanghai, China The Deng laboratory at CIMR is committed to elucidating the role of B cell heterogeneity in tumor development, metastasis and responses to immunotherapy. Our objective is to achieve a deeper understanding of the pathological mechanism associated B cells and tertiary lymphoid structures in prevalent solid tumors, as well as develop potential therapeutic strategies aimed at reprogramming B cell fate.

Majors for Enrollment: Oncology Immunology Biochemistry and Molecular Biology  B.S. in Life Science, Central China Normal University, ChinaPh.D. in Microbiology, Institut Pasteur of Shanghai, Chinese Academy of Sciences, China 2024.6-PresentAssistant investigator, Chinese Institutes for Medical Research, Beijing, China2021.9-2024.5Senior Research Scientist, Memorial Sloan Kettering Cancer Center, USA2016.8-2021.8Research Scholar, Memorial Sloan Kettering Cancer Center, USA The Deng laboratory focused on the mechanistic understanding of immune regulation in diseases such as cancer, tissue damage, and neurodegenerative diseases, with a particular focus on macrophage biology in these contexts, to develop mechanism-based intervention approaches to improve disease treatment.

Majors for Enrollment: Biochemistry and Molecular Biology  B.S. in Food Science and Technology, Jiangnan University, ChinaPh.D. in Biotechnology, Peking University & National Institute of Biological Sciences, Beijing, China 2025-PresentAssistant Investigator, Chinese Institutes for Medical Research, Beijing, China2024-2025Associate Research Professor, Westlake University School of Life Sciences, China2016-2023Senior Research Scientist, University of Texas Southwestern Medical Center, USA2012-2016Postdoctoral Fellow, Johns Hopkins University School of Medicine, USA2011-2012Postdoctoral Fellow, National Institute of Biological Sciences, Beijing, China The Pengfei Guo laboratory at CIMR works on uncovering the molecular and genetic mechanisms that regulate tissue growth and organ size control, as well as understanding how dysregulation of these processes contributes to human diseases. By utilizing various model systems and integrating cutting-edge techniques in genetics, cell biology, and bioinformatic, we aim to elucidate fundamental biological principles and identify novel pathways involved in disease pathogenesis. Ultimately, our goal is to leverage these discoveries to develop innovative diagnostic tools and effective treatment strategies for diseases, including cancer and developmental disorders.

Majors for Enrollment: Neurobiology  2024-PresentAssociate Investigator, Chinese Institutes for Medical Research, Beijing, China2024-PresentProfessor, Capital Medical University, China2018-2022Associate Professor, Molecular Medicine and Neuroscience, Scripps Research, USA2012-2018Assistant Professor, Molecular Medicine and Neuroscience, Scripps Research, USA2012Postdoctoral Fellow, Harvard Medical School, USA (Advisor: Loren Walensky)2005-2012Postdoctoral Fellow, The Rockefeller University and the Howard Hughes Medical Institute (HHMI), USA (Advisor: Rod MacKinnon) The Hansen Laboratory at CIMR focuses on studying the signaling of excitable cells in their native three-dimensional state to better understand the molecular basis of human disease.

Majors for Enrollment: Immunology Oncology Pathogenic Biology Biochemistry and Molecular Biology  2024-PresentAssistant Investigator, Chinese Institutes for Medical Research, Beijing, China2023-2024Senior Staff Scientist, Harvard Medical School affiliated Boston Children's Hospital and the Broad Institute, USA2017-2022Postdoctoral Associate, Scripps Research Institute, USA2013-2017Postdoctoral Associate, National Institute of Biological Science, Beijing, China The He laboratory at CIMR will fully utilize and continuously optimize the protein in vivo evolution platform based on the B cell germinal center to develop a series of best-in-class or first-in-class protein biologics, as well as their derived therapeutic products such as liposome nanoparticles and oncolytic viruses.

Majors for Enrollment: NeurobiologyBiochemistry and Molecular Biology Oncology  B.S. in Biology, Wuhan University, ChinaPh.D. in Biology, Tsinghua University, China 2024.6-PresentJunior Investigator, Chinese Institutes for Medical Research, Beijing, China2018.12-2024.5Postdoctoral Fellow, University of Texas Southwestern Medical Center, USA The Huang laboratory at CIMR mainly studies the physiological functions of heat shock protein 40s (HSP40s) in critical biological pathways including genome maintenance, innate immunity and glucose metabolism, and their implications in pathogenesis of human diseases, such as cancer, autoimmune disease and metabolic disorder.  

Majors for Enrollment: Immunology Pathogenic Biology Biochemistry and Molecular Biology  B.S. in Pharmaceutical Sciences, Peking University, ChinaM.S. in Pharmacology, Peking University, ChinaPh.D. in Pharmacology and Molecular Sciences, Johns Hopkins University, USA 2025.2-PresentAssistant Investigator, Chinese Institutes for Medical Research, Beijing, China2022.2-2025.2Postdoctoral Fellow, Harvard Medical School and Brigham and Women’s Hospital, USA The Jiang laboratory at CIMR is dedicated to using chemical biology approaches to decode the functions of protein post-translational modifications (PTMs) in cancer and other diseases, with a focus on advancing innovative therapeutic strategies.

Majors for Enrollment: NeurobiologyImmunology Biochemistry and Molecular Biology  B.S. in Biotechnology, Wu Yuzhang Honors College, Sichuan University, ChinaPh.D. in Biochemistry and Molecular Biology, The Institute of Biophysics, Chinese Academy of Sciences, China 2025.5-PresentAssistant Investigator, Chinese Institutes for Medical Research, Beijing, China2023.9-2025.5Instructor, Harvard Medical School, Boston Children’s Hospital, USA2016.7-2023.9Postdoc Researcher, Harvard Medical School, Boston Children’s Hospital and Howard Hughes Medical Institute, USA The Leng Laboratory at CIMR investigates the molecular mechanisms by which FoxP3 regulates the gene network of regulatory T cells (Tregs), with the goal of developing drugs that target FoxP3 to modulate Treg activity, offering potential therapeutic strategies for autoimmune diseases and cancer.

Majors for Enrollment: Immunology Oncology Biochemistry and Molecular Biology  Professor Chuanyuan Li received his bachelor’s degree from the University of Science and Technology of China, his Ph.D. in Cancer Biology from Harvard University, and his postdoctoral studies at Harvard. He worked as an Assistant Professor, Associate Professor, and Full Professor at Duke University School of Medicine in the United States beginning in 1997. He served as a lifelong professor in Cancer Biology, Pharmacology, and Dermatology and was the Deputy Director of Research in the Dermatology Department.Now Professor Li is Distinguished Investigator and Director of Chinese Institute for Molecular and Cellular Therapeutics, Chinese Institutes for Medical Research, Beijing. Over the years, he has been involved in research on the mechanisms of tumor development, resistance mechanisms of tumors to radiation and chemotherapy, and the discovery of new molecular targets to enhance tumor immunotherapy. In these fields, he has achieved numerous innovative and impactful research results. He has over 150 peer-reviewed scholarly articles, many of which have appeared in prestigious journals such as Nature, Nature Medicine, Cell Stem Cell, and Molecular Cell, among others. Two innovative achievements in tumor immunotherapy from his research have entered the clinical trial phase.