Laboratory Introduction

Dr. Zhiqiang Yan obtained his bachelor's degree from Fudan University in 2004, Then, he pursued his Ph.D. degree in Neurobiology, Institute of Neuroscience, Chinese Academy of Sciences, National Institute of Biology Sciences, Beijing & Institute of Biophysics, Chinese Academy of Sciences from 2004-2009. He received postdoctoral training in both Lily Jan' group and Yuh Nung Jan' group at Howard Hughes Medical Institute &University of California at San Francisco, San Francisco, USA. In 2013, he was appointed as a professor in Fudan University. Then, he joined Shenzhen Bay Laboratory as a senior principal investigator at 2020 and appointed as deputy director at 2022. Then, he joined Capital Medical University as the Dean and doctoral supervisor of the school of Basic Medical Sciences, and joined the Chinese Institutes for Medical Research (CIMR) in Beijing as a senior principal investigator and director of the Institute for Medical Physiology at 2024. He has won honors such as Human Frontier Science Program (HFSP) Long-term Fellowship (2010-2013), the Program for Professor of Special Appointment (Eastern Scholar of Shanghai) (2014), the Shanghai Rising-Star Program (2014), etc. Dr. Yan has published papers as corresponding author (including co-authors) in journals including Neuron, Nature Structural & Molecular Biology, PNAS, Nature Communications, eLife, Cell Reports, etc. He was supported by 4 National Key Research and Development Projects of China and 2 general programs of the National Natural Science Foundation of China.

The Yan laboratory studies sensory neurobiology, focuses on identifying the receptors and neural circuits for sensation and interoception, studies their working mechanism and related the diseases in sensory system.

a. Identify the receptors for hearing, touch, pain, and thirst sensation, study the gating and assembly of the related sensory transduction complex, and explore their functions in various physiological processes, such as digestion and immunity.

b. Analysis of the protein structures of sensory receptor ion channels and their complexes, as well as the examination of ion permeability and gating mechanisms.

c. Map the critical neuronal groups and circuits for sensation and interoception such as touch, pain, vestibular and thirst sensation.

d. Study pathogenic mechanism, diagnosis and treatment of congenital hearing loss.

Genome Research, 2022, 32: 1573-1584. PMID: 35760561

Nature Communications, 2022, 13: 3814. PMID: 35780140

PNAS, 2021, 118: e2106459118. PMID: 34848538

eLife, 2021, 10: e58388. PMID: 34101577

Neuron, 2020, 105: 310–321. PMID: 31761710

Nature Structural & Molecular Biology, 2018, 25: 850-858. PMID: 30190597

Cell Reports, 2018, 23: 23-31. PMID: 29617663

Open position

Research Assistant

Main Responsibilities:

Qualifications:

Welfare Treatment

How to apply

To apply, please send personal resume, research interest or plan, and other materials demonstrating research capabilities to yan_lab@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.

Contact person: Zhiqiang Yan

Contact address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing

This recruitment is valid for the long term until a suitable candidate is recruited.