CIMR-Postdoctoral Fellows Positions in Liu Lab

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Postdoctoral Fellows Positions in Liu Lab

Date：2024-12-12

Laboratory Introduction

Dr. Shiyu Liu graduated from the School of Life Sciences at Peking University in 2016 and earned his Ph.D. degree in Computational Biology and Bioinformatics from Duke University in 2021. Following his doctoral studies, he continued as a postdoctoral researcher at Duke University. In January 2025, Dr. Liu will establish his independent laboratory at the Chinese Institute for Medical Research, Beijing (CIMR).

A. Research Direction

The laboratory will focus on metabolic flux analysis as its core technology, with the goal of developing innovative methods for deciphering metabolic activities in complex organisms. By integrating metabolic flux analysis with diverse physiological, multi-omics, and genetic technologies, the lab aims to:

1. Investigate how varying nutritional conditions influence metabolic activities across multiple organs in animals, and explore strategies for actively modulating metabolic pathways to restore or optimize dysfunctional metabolic states.

2. Utilize spatial metabolomics technologies to examine tissue-level metabolic heterogeneity, revealing the link between this heterogeneity and the normal functioning of organs.

Through these approaches, the lab aspires to quantitatively uncover the fundamental principles governing metabolic networks in living systems and design novel therapeutic strategies to address a wide range of metabolic diseases.

B. Representative Publications

Liu et al., 2020, Cell Metabolism, PMID: 32961109

Wei, Liu et al., 2024, Nature Aging, PMID: 39060538

Liu et al., 2024, Nature Metabolism, PMID: 39455888

Open position

Postdoctoral Researcher

Main Responsibilities:

a. Conduct independent research under the mentorship of the PI, advancing the lab’s research projects.

b. Provide guidance and mentorship to graduate students and contribute to preparation of manuscripts and grant applications.

Qualifications:

a. Algorithm Development: A background in Computer Science, Machine Learning, Bioinformatics, or related computational fields.

Biological Research Applications: A background in Life Sciences, Biomedical Sciences, or related fields.

Candidates should have recently obtained or be nearing completion of a Ph.D.

b. A demonstrated record of first-author publications in leading journals or upcoming publications, highlighting the ability to conduct independent research.

c. Strong research passion, a rigorous scientific attitude, and the ability to work collaboratively within a multidisciplinary team.

d. Algorithm Development: Experience in numerical optimization or machine learning algorithm development is preferred.
Biological Research Applications: Experience in metabolomics, with an emphasis on spatial metabolomics, is preferred.

e. Proficiency in English for academic writing, communication, and daily interactions.

Welfare Treatment

a. Competitive Salary
A highly competitive salary, commensurate with the candidate’s experience and qualifications, will be offered (details to be discussed during the interview).

b. Comprehensive Benefits
Full coverage of social insurance, paid annual leave, regular health check-ups, and supplemental medical insurance.

c. Professional Development
Opportunities for personal and professional growth, including access to job-related training programs and skill enhancement resources.

Application Process

Application Materials

Please submit a CV, a statement of research interests or plans, and the names and contact information of 2–3 referees who can attest to your research capabilities.

Submission

Email all required application materials to shiyu.liu@cimrbj.ac.cn with the subject line formatted as "[Applicant Name] + [Position Applied For]".

Contact person: Dr. Shiyu Liu

Contact address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing

This job posting remains open until suitable candidates are found.