CIMR-Open Positions for Lab Manager in Hansen Lab

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Open Positions for Lab Manager in Hansen Lab

Date：2025-01-08

Laboratory Introduction

The Hansen Laboratory at CIMR focuses on studying the signaling of excitable cells in their native three-dimensional state to better understand the molecular basis of human disease. By investigating these molecular mechanisms, we aim to elucidate disease progression and develop therapies to prevent or mitigate its impact.

A. Major Research Projects

1. Establishing the molecular basis for membrane-mediated anesthesia using super-resolution imaging and spatial biology.

2. Investigating the molecular role of cholesterol in driving inflammatory diseases, including Alzheimer’s disease and chronic pain.

3. Developing non-addictive analgesics (pain medications) using novel drug discovery assays.

4. Uncovering the molecular basis of membrane-mediated mechanosensation at low thresholds.

B. Major Contributions

1. Identified a membrane-mediated mechanism of anesthetic action in mammalian cells and in fruit fly (PNAS, 2020)

2. Established a membrane-mediated mechanism of mechanosensation regulating a potassium channel (eLife, 2024; Nature Communications, 2016)

3. Identified astrocyte cholesterol as a regulator of amyloid production in Alzheimer’s Disease (PNAS, 2021)

4. Demonstrated that signaling lipids act as direct agonists of ion channels (BBA, 2016; Nature, 2011)

C. Representative Publications

eLife, 2024, 12: RP89465. DOI: 10.7554/eLife.89465

Pharmacology & Therapeutics, 2023, 249: 108486. DOI: 10.1016/j.pharmthera.2023.108486

The Journal of biological chemistry, 2023, 299: 104763. DOI: 10.1016/j.jbc.2023.104763

PNAS, 2021, 118: e2102191118. DOI: 10.1073/pnas.2102191118

PNAS, 2020, 117: 13757–13766. DOI: 10.1073/pnas.2004259117

Open position

Laboratory Manager

Main Responsibilities:

a. Order and manage laboratory consumables and reagents and prepare commonly used buffers and solutions.

b. Laboratory daily management and expense accounting and reimbursement.

c. Arrange lab meetings and other routine activities.

Qualifications:

a. Have a bachelor's degree or above degree in life science- or medicine-related majors.

b. Have excellent communication skills and teamwork skills.

c. Proficient in English and Chinese reading, writing, and daily communication.

d. Familiar with daily office software.

e. Priority will be given to applicants with laboratory management experience.

Welfare Treatment

a. Provide competitive salary based on the applicant’s work experience and ability (salary negotiable).

b. Provide social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.

c. Support career development and provide relevant professional guidance.

How to apply

Please send a resume, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to shansen@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.

Contact person: Scott Hansen

Contact address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing

This job posting remains open until suitable candidates are found.