The Yun group leverages salamander systems in order to unveil the cellular and molecular mechanisms underlying organ regeneration, determine how phylogenetic changes affect regenerative potential, and probe the links between regeneration and ageing. We employ two genetically-tractable salamander models, the axolotl (Ambystoma mexicanum) and the Iberian ribbed newt (Pleurodeles waltl), known for their extreme regenerative abilities and negligible senescence traits. Combining state-of-the-art genetics, cell and molecular biology approaches, advanced imaging, multiomics and cross-species comparative studies, we aim to uncover fundamental principles of regeneration and ageing towards basic and therapeutic applications. Further information can be found at www.theyunlab.com.
We offer an international, creative, science-driven and inspiring environment. The successful candidates will benefit from our large network of collaborations (Germany, UK, USA) and have immediate opportunities to contribute to international projects. Our lab is located at the newly built Institute for Regenerative Biology and Medicine, Chinese Institutes for Medical Research.
Open Positions
Bioinformatician
We are seeking a highly motivated bioinformatician to join our efforts to unravelling the links between regeneration and ageing.
Main Responsibilities:
a. Design and conduct bioinformatic analyses of data at single cell and bulk level, including transcriptomic, epigenetic (e.g. DNAm arrays, genomic data) and proteomic datasets, including mRNA sequencing data generated via the 10XMultiome workflow and Illumina sequencing.
b. Conduct cross-species single cell analyses.
c. Analyse and interpret spatial transcriptomics.
d. Contribute to hypothesis generation, experimental design, analytical pipeline documentation, research presentations and manuscript preparation.
e. Provide training/guidance to other team members.
f. Balance independent work and team collaboration.
Qualifications:
Candidates should have a degree in bioinformatics or a related field, strong theoretical knowledge and experience in bioinformatics, particularly single cell data and spatial transcriptomics analyses. Fluency in spoken and written English is required. Prior experience in the fields of Regeneration, Aging or Evolutionary biology is a bonus.
Welfare Treatment
a. Competitive salary based on the job applicant's work experience and abilities (salary negotiable).
b. Social insurance, paid annual leave, physical examination and supplementary medical insurance, etc.
c. Opportunities for career development and available professional guidance.
How to Apply
Please send a resume, a brief summary of research interests & key accomplishments, the names and contacts of 3 referees and other materials demonstrating research capabilities to max.yun@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.
Contact person: Max H. Yun
This recruitment is valid for the long term until a suitable candidate is recruited.
10 Xitoutiao, Youanmen Wai, Fengtai District, Beijing 100069, China
010-86738999
cimr@cimrbj.ac.cn
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