Institute for Cancer Research, Chinese Institutes for Medical Research, Beijing, China
E-mail: zhangyu@cimrbj.ac.cn

Education
BS, Biochemistry, Beijing Normal University
MS, Biochemistry and Molecular Biology, Beijing Normal University
PhD, Genetics, University of Basel, Friedrich Miescher Institute for Biomedical Research, Switzerland
Postdoctoral training, immune Disease Institute, the Children’s Hospital Boston, Harvard Medical School, Boston, MA, USA

 

Functional genomics, immunology, tumor immunotherapy

Representative publications
Hu Q, Hong Y, Qi P, Lu G, Mai X, Xu S, He X, Guo Y, Gao L, Jing Z, Wang J, Cai T, Zhang Y. Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling. Nat Commun. 2021;12(1):2186.
Hu Q, Hong Y, Qi P, Lu G, Mai X, Xu S, He X, Guo Y, Gao L, Jing Z, Wang J, Cai T, Zhang Y. Atlas of breast cancer infiltrated B-lymphocytes revealed by paired single-cell RNA-sequencing and antigen receptor profiling. Nat Commun. 2021;12(1):2186.
Duan J, Lu G, Hong Y, Hu Q, Mai X, Guo J, Si X, Wang F, Zhang Y. Live imaging and tracking of genome regions in CRISPR/dCas9 knock-in mice. Genome Biol. 2018;19(1):192.
Duan J, Lu G, Xie Z, Lou M, Luo J, Guo L, Zhang Y. Genome-wide identification of CRISPR/Cas9 off-targets in human genome. Cell Res. 2014;24(8):1009-12.
Zhang Y, McCord RP, Ho YJ, Lajoie BR, Hildebrand DG, Simon AC, Becker MS, Alt FW, Dekker J. Spatial organization of the mouse genome and its role in recurrent chromosomal translocations. Cell. 2012;148(5):908-21.
Chiarle R, Zhang Y, Frock RL, Lewis SM, Molinie B, Ho YJ, Myers DR, Choi VW, Compagno M, Malkin DJ, Neuberg D, Monti S, Giallourakis CC, Gostissa M, Alt FW. Genome-wide translocation sequencing reveals mechanisms of chromosome breaks and rearrangements in B cells. Cell. 2011;147(1):107-19.