Director, Beijing Ditan Hospital Research Center
Vice Chair
Department of Oncology, Capital Medical University, Beijing, China
E-mail: xiwang@ccmu.edu.cn

Education
BM (Bachelor of Medicine), Peking University (Beijing Medical University)
MS, Basic Medicine, Peking University (Beijing Medical University)
PhD, Cellular and Developmental Biology, Pennsylvania State University, USA
Postdoctoral training, Harvard University Medical School, USA

 

Chair, Committee of Infectious Diseases, Beijing Society for Chronic Illness
Executive Editor, Journal of Biological Methods
Editorial Board: Cancer Biology & Medicine, Aging Medicine

 

Research interests
Epigenetics in cancer immunotherapy

Representative publications
Yu M, Su Z, Huang X, Zhou Y, Zhang X, Wang B, Wang Z, Liu Y, Xing N, Xia M, Wang X. Histone methyltransferase Ezh2 negatively regulates NK cell terminal maturation and function. J Leukoc Biol. 2021;110(6):1033-1045.
Li Y, Yu M, Yin J, Yan H, Wang X. Enhanced Calcium Signal Induces NK Cell Degranulation but Inhibits Its Cytotoxic Activity. J Immunol. 2022;208(2):347-357.
Huang S, Li Z, Wu Z, Liu C, Yu M, Wen M, Zhang L, Wang X. DDAH2 suppresses RLR-MAVS-mediated innate antiviral immunity by stimulating nitric oxide-activated, Drp1-induced mitochondrial fission. Sci Signal. 2021;14(678):eabc7931.
Liu C, Huang S, Wang X, Wen M, Zheng J, Wang W, Fu Y, Tian S, Li L, Li Z, Wang X. The Otubain YOD1 Suppresses Aggregation and Activation of the Signaling Adaptor MAVS through Lys63-Linked Deubiquitination. J Immunol. 2019;202(10):2957-2970.
Yin J, Leavenworth JW, Li Y, Luo Q, Xie H, Liu X, Huang S, Yan H, Fu Z, Zhang LY, Zhang L, Hao J, Wu X, Deng X, Roberts CW, Orkin SH, Cantor H, Wang X. Ezh2 regulates differentiation and function of natural killer cells through histone methyltransferase activity. Proc Natl Acad Sci U S A. 2015;112(52):15988-93.