Laboratory Introduction
The laboratory of Shao-Cong Sun at the Chinese Institutes for Medical Research (CIMR) is recruiting motivated Postdoctoral Fellows and Research Associate Investigators to conduct basic and translational research in Cancer Immunology and Autoimmunity. A major focus of the lab is to study the molecular mechanisms that regulate T cell activation, differentiation, effector function, and exhaustion using a variety of cutting-edge techniques, such as signal transduction, CRISPR library screening, single-cell RNA sequencing, and knockout mouse models. Our recent work also includes the use of bioinformatics to analyze tumor sequencing databases of cancer patients, identify cancer immunomodulators, and then conduct mechanistic studies using mouse models. Autoimmune studies include mouse models of multiple sclerosis, SLE, and colitis. Professor Sun's team has made many significant contributions in this field, including the discovery of key factors regulating T cell functions in autoimmunity and cancer immunity. Our work also has strong translational potential and plays an important guiding role in drug development and disease treatment. The laboratory also uses mouse models of cancer immunotherapy to conduct translational studies and explore improved methods of immunotherapy.
Representative Publications
Nature Cell Biology 24: 1165-1176, 2022, PMID: 35773432
Nature Immunology 22: 193-204, 2021, PMID: 33398181
Nature Cell Biology 21: 1604-1614, 2019, PMID: 31792381
Nature Immunology 20: 879-889, 2019, PMID: 31182807
Nature Immunology 19: 1224-1235, 2018, PMID: 30250187
Nature 545: 365-369, 2017, PMID: 28489822
Nature Immunology 17: 259-268, 2016, PMID: 26808229
Nature Immunology 15: 562-570, 2014, PMID: 24777531
Immunity 40: 692-705, 2014, PMID: 24792914
Nature Medicine 19: 595-602, 2013, PMID: 23603814
Nature 494: 371-374, 2013, PMID: 23334419
Open position
Postdoctoral Fellows / Research Associate Investigators
Main Responsibilities:
a. Carrying out research projects independently.
b. Assisting PI to mentor graduate student.
Qualifications:
a. With research background in immunology related biomedical fields, either about to obtain or having already obtained a doctoral degree; postdoctoral experience is required for research associate investigator position.
b. With motivation and ability to independently carry out research projects and supervise graduate students, and have strong motivation in scientific research.
c. Proficient in English reading, writing, and daily communication; capable of writing papers in English.
d. Those with solid background in immunology, bioinformatics, mouse models of cancer immunity or autoimmunity, or CRISPR screen will be given priority.
Welfare Treatment
How to apply
To apply, please send personal resume, research interest or plan, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to ssun@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.
Contact person: Dr. Sun
Contact address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing
This recruitment is valid for the long term until a suitable candidate is recruited.