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Postdoctoral Fellows Positions in Guo Lab
Date:2025-04-29

Laboratory Introduction

The Guo laboratory at CIMR works on uncovering the molecular and genetic mechanisms that regulate tissue growth and organ size control, as well as understanding how dysregulation of these processes contributes to human diseases.

 

A. Major Research Projects

The Guo lab will use various model systems and integrate cutting-edge techniques in genetics, cell biology, and bioinformatic, with the aims of elucidating fundamental biological principles and identifying novel pathways involved in disease pathogenesis.

a. Conducting genome-wide screening in Drosophila and mouse models to identify key genes that regulate tissue growth and organ size.
b. Investigating the role of tissue mechanics in regulating tissue growth and how physical forces and mechanical properties influence cellular behavior. Additionally, we explore how the tumor microenvironment’s physical properties affect tumor growth and immune response.
c. Investigating the role of the Hippo signaling pathway in normal developmental processes and how its disruption contributes to congenital developmental diseases, with a particular focus on neurodevelopmental disorders.

 

B. Representative Publications

Science. 2024. 385(6709):eadf4478. PMID: 39116228.

eLife. 2019. 22:8:e38843. PMID: 30901309.

PNAS. 2010. 107(42):18016–18021. PMID: 20921409.

 

Open position

Postdoctoral Researcher

Main Responsibilities:

a. Conducting research projects independently.

b. Assisting PI to mentor graduate students, write grant proposals and manuscripts.

 

Qualifications

a. Backgrounds in biology or biomedical fields. Either about to obtain a Ph.D. or recently obtained a Ph.D. degree (ideally within the last 2 years). 

b. Candidates with experience in mouse tumor models, developmental biology, or genome-wide CRISPR screening are preferred.

c. Proven ability to conduct independent research, demonstrated by a first-author publication in a reputable journal in the field (or a paper accepted for publication).

d. Proficient in English reading, writing, and daily communication. Capable of writing papers in English.

 

Welfare Treatment

a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).

b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.

c. Opportunities for career development and available professional guidance.

 

How to apply

To apply, please send personal resume, research interest or plan, the names and contacts of 2-3 referees and other materials demonstrating research capabilities to guopengfei@cimrbj.ac.cn, and indicate the applicant's name and specific job position in the email subject.

 

Contact person: Pengfei Guo

 

Contact address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing

 

This recruitment is valid for the long term until a suitable candidate is recruited.