Laboratory Introduction
The Deng laboratory focused on the mechanistic understanding of immune regulation in diseases such as cancer, tissue damage, and neurodegenerative diseases, with a particular focus on macrophage biology in these contexts, to develop mechanism-based intervention approaches to improve disease treatment.
Representative Publications：
*: Co-first author; #: Co-corresponding author
Aggarwal SS#, Andreani C#, Deng Z#, Frede J#, Kameneva P#, Kovatcheva M#, Micevic G#, Nicolson F#, Puschhof J#, Roberts M#, Wang G#, Watson DC#. The 2024 generation. Nature Cancer, 2024, 5: 1774–1778. DOI: 10.1038/s43018-024-00866-2.
Deng Z, Loyher PL, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Alberdi A, Massague J, Sun J, Benezra R, Glass CK, Elemento O, Iacobuzio-Donahue CA, Geissmann F#. The nuclear factor ID3 endows macrophages with a potent anti-tumor activity. Nature, 2024, 626: 864-873. DOI: 10.1038/s41586-023-06950-4.
Deng Z, Ma S, Zhou H, Zang A, Fang Y, Li T, Shi H, Liu M, Du M, Taylor PR, Zhu HH, Chen J, Meng G, Li F, Chen C, Zhang Y, Jia XM, Lin X, Zhang X, Pearlman E, Li X, Feng GS, Xiao H#. Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses. Nature Immunology, 2015, 16: 642-652. DOI: 10.1038/ni.3155.
Open position
Postdoctoral Researcher
We are seeking motivated and talented individuals to join our dynamic research team in the fields of tumor immunology.
Responsibilities involve leading independent research projects, assisting in student mentoring, and contributing to grant and manuscript preparation. Applicants must hold or soon obtain a Ph.D. in immunology, cancer biology, biochemistry, cell biology, or related fields. The ideal candidate will demonstrate scientific curiosity, a strong work ethic, first-author publications in reputable journals, and the ability to work independently. Fluency in written and spoken English for academic purposes is required.
Welfare Treatment
a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).
b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c. Opportunities for career development and available professional guidance.
How to apply
We offer a collaborative and supportive research environment with opportunities for professional growth. Interested candidates are invited to submit their CV, cover letter, and contact information for references to zdeng@cimrbj.ac.cn.
Contact Person: Dr. Deng
Contact address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing
This recruitment is valid for the long term until a suitable candidate is recruited
10 Xitoutiao, Youanmen Wai, Fengtai District, Beijing 100069, China
010-86738999
cimr@cimrbj.ac.cn
中文
