Laboratory Introduction
The Deng laboratory focused on the mechanistic understanding of immune regulation in diseases such as cancer, tissue damage, and neurodegenerative diseases, with a particular focus on macrophage biology in these contexts, to develop mechanism-based intervention approaches to improve disease treatment.
Representative Publications：
*: Co-first author; #: Co-corresponding author
Aggarwal SS#, Andreani C#, Deng Z#, Frede J#, Kameneva P#, Kovatcheva M#, Micevic G#, Nicolson F#, Puschhof J#, Roberts M#, Wang G#, Watson DC#. The 2024 generation. Nature Cancer, 2024, 5: 1774–1778. DOI: 10.1038/s43018-024-00866-2.
Deng Z, Loyher PL, Lazarov T, Li L, Shen Z, Bhinder B, Yang H, Alberdi A, Massague J, Sun J, Benezra R, Glass CK, Elemento O, Iacobuzio-Donahue CA, Geissmann F#. The nuclear factor ID3 endows macrophages with a potent anti-tumor activity. Nature, 2024, 626: 864-873. DOI: 10.1038/s41586-023-06950-4.
Deng Z, Ma S, Zhou H, Zang A, Fang Y, Li T, Shi H, Liu M, Du M, Taylor PR, Zhu HH, Chen J, Meng G, Li F, Chen C, Zhang Y, Jia XM, Lin X, Zhang X, Pearlman E, Li X, Feng GS, Xiao H#. Tyrosine phosphatase SHP-2 mediates C-type lectin receptor-induced activation of the kinase Syk and anti-fungal TH17 responses. Nature Immunology, 2015, 16: 642-652. DOI: 10.1038/ni.3155.
Open position
Research Assistant
We are seeking motivated and talented individuals to join our dynamic research team in the fields of tumor immunology.
Responsibilities include conducting independent or collaborative researcsh projects and managing daily lab operations and administrative tasks. Candidates should possess a Master’s degree (or a Bachelor’s degree with substantial research experience) in biology, basic medicine, or related disciplines. Practical experience in animal, cellular, or molecular experiments is required. Strong sense of responsibility, teamwork skills, and proficiency in English communication and writing are essential.
Welfare Treatment
a. Competitive salary based on the applicant’s work experience and ability (salary negotiable).
b. Social insurance and housing fund, supplementary medical insurance, physical examination and paid annual leave.
c. Opportunities for career development and available professional guidance.
How to apply
We offer a collaborative and supportive research environment with opportunities for professional growth. Interested candidates are invited to submit their CV, cover letter, and contact information for references to zdeng@cimrbj.ac.cn.
Contact Person: Dr. Deng
Contact address: No.10 Xitoutiao, Youanmenwai, Fengtai District, Beijing
This recruitment is valid for the long term until a suitable candidate is recruited
10 Xitoutiao, Youanmen Wai, Fengtai District, Beijing 100069, China
010-86738999
cimr@cimrbj.ac.cn
中文
