CIMR-Wayne W. Zhang

Research Group

Wayne W. Zhang

waynezhang(at)cimrbj.ac.cn

Distinguished Investigator

Vascular Surgery, Cardiovascular Diseases,

R&D of Minimally Invasive Cardiovascular Devices,

3D Bioprinting, Organoids and Organs-on-a-Chip

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waynezhang(at)cimrbj.ac.cn

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B.S. in Surgery, Henan Medical University, China

M.S. in Surgery, Henan Medical University, China

M.D. in Surgery, State University of New York at Buffalo, USA

Work Experience

2024-Present

Distinguished Investigator and Director, Independent Cardiovascular Research Lab, Chinese Institutes for Medical Research, Beijing, China

2024-Present

Chair Professor, Capital Medical University, China

2023-Present

Clinical Professor, University of Washington, USA

2017-2023

Professor and Section Chief, University of Washington, USA

2015-2017

Professor and Chief, Division of Vascular and Endovascular Surgery; Vice Chairman of Department of Surgery, Louisiana State University Health Sciences Center-Shreveport, USA

2010-2015

Associate Professor and Chief, Division of Vascular and Endovascular Surgery, Department of Surgery, Louisiana State University Health Sciences Center-Shreveport, USA

2005-2009

Assistant Professor, Loma Linda University, USA

Honors and Awards

2025

5th Annual Innovations in Vascular Surgery and Endovascular Therapies Award, The Frank J Veith International Vascular Society

2024

4th Annual Innovations in Vascular Surgery and Endovascular Therapies Award, The Frank J Veith International Vascular Society

2021-Present

Editor, Annuals of Vascular Surgery

2017-2018

Vice President, International Society for Vascular Surgery

2016

Special Recognition Award, VEITH Symposium

2015

Tenure Professor, Louisiana State University

2014-Present

Distinguished Fellow, Society for Vascular Surgery (DFSVS)

2009-Present

Fellow, American College of Surgeons (FACS)

Research Interests

Zhang Lab is focusing on:

1. basic science studies on the etiologies, pathogenesis, pathophysiological changes of cardiovascular diseases.

2. cardiovascular organoids and organ-on-a-chip, utilizing advanced 3D bioprinting, stem-cell-derived, or tissue-engineered models to mimic human heart and vessel physiology for improved disease modeling, drug testing, and personalized treatment.

3. development and translation of innovative technologies for early diagnosis and minimally invasive management of cardiovascular diseases. Two of our novel devices are currently under investigation with multi-center clinical trials.

Major Contributions

1. First use of a new negative pressure system for prevention and management of vascular surgical wound complications

2. Developed a new technique using physician modified re-constrainable endograft system for complex abdominal and thoracoabdominal aneurysms

3. Invented ZIPPER stentgraft system for mini-invasive total transfemoral endovascular repair of aortic arch pathologies

4. Invented a novel percutaneous stenting system for mini-invasive endovascular treatment of carotid stenosis

5. Invented an endovascular aneurysm repair covered stent system to prevent endoleaks

Representative Publications *：Co-first author; #：Co-corresponding author

Zhang W, Mei F, Jiang P, Cui Y, Zhang W. Real-world treatment strategies for symptomatic chronic internal carotid artery occlusion. Journal of Vascular Surgery, 2025, 81: 510-511. DOI: 10.1016/j.jvs.2024.09.027.

Fu W, Dong H, Hu J, Zhang W. Total Percutaneous Transfemoral Endovascular Treatment of Non-A-non-B Aortic Dissection. J Am Coll Cardiol Case Reports, 2025, 30: 102756. DOI: 10.1016/j.jaccas.2024.102756.

Jiang C, Zhao Y, Zhang W, Chen Z, Zeng Q, Li F. Recanalization of superficial femoral artery chronic total occlusion through retrograde popliteal approach recanalization of superficial femoral artery chronic total occlusion. Heliyon, 2024, 10: e30872. DOI: 10.1016/j.jvs.2020.12.050.

Menard MT, Farber A, Powell RJ, Rosenfield K, Conte MS, Hamza TH, …, Zhang W, …, BEST-CLI Investigators. Quality of Life in Patients With Chronic Limb-Threatening Ischemia Treated With Revascularization. Circulation, 2024, 149: 1241-1253. DOI: 10.1161/CIRCULATIONAHA.123.065277.

Mei F, Zhang W, Jiang P, Tan C, Cui Y, Fan J, Zhang W. Comparison of the treatment strategies for symptomatic chronic internal carotid artery occlusion. Journal of Vascular Surgery, 2024, 18: S0741-5214(24)01533-7. DOI: 10.1016/j.jvs.2024.05.062.

Dong H, Fu W, Zhang W. First-in-man ZIPPER™ endograft system for the treatment of symptomatic aortic arch intramural haematoma. European Heart Journal, 2023, 7: ytad574. DOI: 10.1093/ehjcr/ytad574.

Farber A, Menard MT, Conte M, Kaufman JA, Powell RJ, Choudhry NK, …, Zhang W, …, et al. Surgery or Endovascular Therapy for Chronic Limb-Threatening Ischemia. The New England Journal of Medicine, 2022, 387: 2305-2316. DOI: 10.1056/NEJMoa2207899.

Cao Z, Zhu R, Ghaffarian A, Wu W, Weng C, Chen X, Shalhub S, Starnes BW, Zhang W. A systematic review and meta-analysis of the clinical effectiveness and safety of unilateral versus bilateral iliac branch devices for aortoiliac and iliac artery aneurysms. Journal of Vascular Surgery, 2022, 76: 1089-1098.e8. DOI: 10.1016/j.jvs.2022.03.005.

Zhang Z, Zhou Y, Lin S, Xiao J, Ai W, Zhang W. Systematic review and meta-analysis of association of prophylactic cerebrospinal fluid drainage in preventing spinal cord ischemia after thoracic endovascular aortic repair. Journal of Vascular Surgery, 2022, 75: 1478-1489.e5. DOI: 10.1016/j.jvs.2021.10.050.

Guo Z, Liu C, Huang K, Yu N, Peng M, Starnes BW, Chow WB, Li Z, Zhang W. Meta-analysis of Re-do Stenting Versus Endarterectomy for In-stent Stenosis Following Carotid Artery Stenting. Journal of Vascular Surgery, 2021, 73: 1282-1289. DOI: 10.1016/j.jvs.2020.07.102.

Mei F, Fan J, Yuan J, Liang Z, Wang K, Sun J, Guan W, Huang M, Li Y, Zhang W. Comparison of Venous Thromboembolism Risks Between COVID-19 Pneumonia and Community-Acquired Pneumonia Patients. Arteriosclerosis, Thrombosis, and Vascular Biology, 2020, 40: 2332-7. DOI: 10.1161/ATVBAHA.120.314779.

Delafontaine JL, Hu B, Tan TW, Tang GL, Starnes BW, Virk C, Chow WB, Zhang W. Outcome Comparison of TEVAR with and without Left Subclavian Artery Revascularization from Analysis of Nationwide Inpatient Sample Database. Annals of Vascular Surgery, 2019, 58: 174-9. DOI:10.1016/j.avsg.2019.01.005.

Dong H, Du T, Premaratne S, Zhao C, Tian Q, Li Y, Yan S, Zhang W. Relationship between ADAMTS4 and Carotid Atherosclerotic Plaque Vulnerability in Humans. Journal of Vascular Surgery, 2018, 67: 1120-1126. DOI: 10.1016/j.jvs.2017.08.075.

Pearce FB, Yang S, Shi R, Tan TW, Zhang W. Circumferential Aortic Endarterectomy Followed With Immediate Infrarenal Clamping May Avoid Suprarenal Clamping During Open Surgery for Juxtarenal Aortoililac Occlusive Disease. Annals of Vascular Surgery, 2016, 34: 48-54. DOI: 10.1016/j.avsg.2016.01.018.

Full List of Publications Can Be Found here