Rinkevich实验室的研究聚焦于组织与器官损伤后的修复与再生机制，旨在揭示其背后的关键细胞与分子调控过程，为临床再生医学和治疗策略的开发提供科学基础。
Correa-Gallegos D*, Ye H*, Dasgupta B*, Sardogan A, Kadri S, Kandi R, Dai R, Lin Y, Kopplin R, Shenai Disha S, Wannemacher J, Ichijo R, Jiang D, Strunz M, Ansari M, Angelidis I, Schiller H, Voltz T, Machens HG, Rinkevich Y. Spatiotemporal differentiation of CD201-expressing fascia progenitors choreographs injury repair. Nature, 2023, 623: 792-802. DOI: 10.1038/s41586-023-06725-x
Fischer A*, Correa-Gallegos D*, Wannemacher J, Christ S, Machens HG, Rinkevich Y. In vivo fluorescent labeling and tracking of Extracellular Matrix. Nature Protocols, 2023, 18: 2876-2890. DOI: 10.1038/s41596-023-00867-y
Gopal KS*, Dai R, Stefanska AM*, Ansari M, Zhao J, Ramesh P, Bagnoli JW, Correa-Gallegos D, Lin Y, Christ S, Angelidis I, Lupperger V, Marr C, Davies LC, Enard W, Machens HG, Schiller HB, Jiang D, Rinkevich Y. Wound infiltrating adipocytes are not myofibroblasts. Nature Communications, 2023, 14: 3020. DOI: 10.1038/s41467-023-38591-6
Fischer A*, Wannemacher J*, Christ S*, Koopmans T, Kadri S, Zhao J, Gouda M, Ye H, Mück-Häusl M, Krenn PW, Machens HG, Fässler R, Neuman PA, Hauck S, Rinkevich Y. Neutrophils direct preexisting matrix in to initiate repair of damaged organs. Nature Immunology, 2022, 23: 518–531. DOI: 10.1038/s41590-022-01166-6
Jiang D*, Christ S*, Correa-Gallegos D*, Ramesh P*, Kalgudde Gopa S, Wannemacher J, Mayr C, Lupperger V, Yu Q, Ye H, Mück-Häusl M, Rajendran V, Wan L, Liu J, Mirastschijski U, Volz T, Marr C, Schiller H, Rinkevich Y. Fascia fibroblasts swarm to drive scar formation through N-cadherin. Nature Communications, 2020, 11: 5653. DOI: 10.1038/s41467-020-19425-1
Fischer A*, Koopmans T*, Ramesh P, Christ S, Strunz M, Aichler M, Feuchtinger A, Walch A, Ansari M, Theis FJ, Schorpp K, Hadian K, Neumann PA, Schiller HB, Rinkevich Y. Post-surgical adhesions are caused by membrane bridges and fusions between mesothelial surfaces. Nature Communications, 2020, 11: 3068. DOI: 10.1038/s41467-020-16893-3
Correa-Gallegos D*, Jiang D*, Christ S, Ramesh P, Ye H, Wannemacher J, Kalgudde Gopal S, Yu Q, Aichler M, Walch A, Mirastschijski U, Volz T, Rinkevich Y. Patch repair of deep wounds by mobilized fascia. Nature, 2019, 576: 287-292. DOI: 10.1038/s41586-019-1794-y
Jiang D*, Correa-Gallegos D*, Christ S, Stefanska A, Liu J, Ramesh P, Rajendran V, Wagner D, Rinkevich Y. Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring. Nature Cell Biology, 2018, 20: 422-431. DOI: 10.1038/s41556-018-0073-8
Tsai JM*, Sinha R*, Seita J, Fernhoff N, Christ S, Koopmans T, Krampitz GW, McKenna KM, Xing L, Shoham M, McCracken M, Joubert LM, Gordon SR, Poux N, Wernig G, Norton JA, Sandholzer M, Sales J, Weissman IL, Rinkevich Y. Surgical adhesions in mice are derived from mesothelial cells and can be targeted by antibodies against mesothelial markers. Science Translational Medicine, 2018, 10: 469. DOI: 10.1126/scitranslmed.aan6735
Rinkevich Y*, Walmsley GG*, Hu MS*, Maan ZN*, Newman AM, Drukker M, Lorenz PH, Weissman IL, Longaker MT. Identification and Targeted inhibition of a Dermal Lineage Responsible for Scarring and Cancer Stroma. Science, 2015, 348: 420-431. DOI: 10.1126/science.aaa2151
北京市丰台区右安门外西头条10号
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