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Gu M*, Zhou X*, Sohn JH, Zhu L, Jie Z, Yang JY, Zheng X, Xie X, Yang J, Shi Y, Brightbill HD, Kim JB, Wang J, Cheng X, Sun SC. NF-κB-inducing kinase maintains T cell metabolic fitness in antitumor immunity. Nature Immunology, 2021, 22:193-204. DOI: 10.1038/s41590-020-00829-6

Zhu L, Li Y, Xie X, Zhou X, Gu M, Jie Z, Ko CJ, Gao T, Hernandez BE, Cheng X, Sun SC. TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis. Nature Cell Biology, 2019, 21:1604-1614. DOI: 10.1038/s41467-018-05097-5

Zhou X, Yu J, Cheng X, Zhao B, Manyam GC, Zhang L, Schluns K, Li P, Wang J, Sun SC.  The deubiquitinase Otub1 controls the activation of CD8(+) T cells and NK cells by regulating IL-15-mediated priming. Nature Immunology, 2019, 20:879-889. DOI: 10.1038/s41590-019-0405-2

Jie Z, Yang JY, Gu M, Wang H, Xie X, Li Y, Liu T, Zhu L, Shi J, Zhang L, Zhou X, Joo D, Brightbill HD, Cong Y, Lin D, Cheng X, and Sun SC.  NIK signaling axis regulates dendritic cell function in intestinal immunity and homeostasis.  Nature Immunology, 2018, 19:1224-1235. DOI: 10.1038/s41590-018-0206-z.

Jin J, Xie X, Xiao Y, Hu H, Zou Q, Cheng X, Sun SC. Epigenetic regulation of the expression of Il12 and Il23 and autoimmune inflammation by the deubiquitinase Trabid.  Nature Immunology, 2016, 17:259-268. DOI: 10.1038/ni.3347

Zou Q, Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC. USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses.  Nature Immunology, 2014, 15:562-570. DOI: 10.1038/ni.2885

Nakaya M, Xiao Y, Zhou X, Chang JH, Chang M, Cheng X, Blonska M, Lin X, Sun SC. Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation.  Immunity, 2014, 40:692-705. DOI: 10.1016/j.immuni.2014.04.007

Jin J, Hu H, Li HS, Yu J, Xiao Y, Brittain GC, Zou Q, Cheng X, Mallette FA, Watowich SS, Sun SC. Noncanonical NF-κB pathway controls the production of type I interferons in antiviral innate immunity.  Immunity, 2014, 40:342-54. DOI: 10.1016/j.immuni.2014.02.006

Xiao Y, Jin J, Chang M, Chang JH, Hu H, Zhou X, Brittain GC, Stansberg C, Torkildsen Ø, Wang X, Brink R, Cheng X, Sun SC. Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation .Nature Medicine, 2013, 19:595-602. DOI: 10.1038/nm.3111

Hu H, Brittain GC, Chang JH, Puebla-Osorio N, Jin J, Zal A, Xiao Y, Cheng X, Chang M, Fu YX, Zal T, Zhu C, Sun SC.  OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3. Nature, 2013, 494:371-374. DOI: 10.1038/nature11831